CAS 115321-98-7

6a-Methylprednisone 21-Acetate

Description:

6a-Methylprednisone 21-Acetate is a synthetic corticosteroid that exhibits anti-inflammatory and immunosuppressive properties. It is derived from prednisone and features a methyl group at the 6a position and an acetate group at the 21 position, which enhances its pharmacological activity. This compound is typically used in the treatment of various inflammatory conditions, autoimmune disorders, and certain types of allergies. Its mechanism of action involves the modulation of gene expression, leading to decreased production of pro-inflammatory cytokines and other mediators. The compound is characterized by its relatively high potency and efficacy in reducing inflammation, making it valuable in clinical settings. Additionally, it may have side effects commonly associated with corticosteroids, such as weight gain, increased blood sugar levels, and potential suppression of the adrenal gland function with prolonged use. As with other corticosteroids, careful monitoring and dosage adjustments are essential to minimize adverse effects while maximizing therapeutic benefits.

Formula: C₂₄H₃₀O₆

InChI: InChI=1/C24H30O6/c1-13-9-16-17-6-8-24(29,20(28)12-30-14(2)25)23(17,4)11-19(27)21(16)22(3)7-5-15(26)10-18(13)22/h5,7,10,13,16-17,21,29H,6,8-9,11-12H2,1-4H3/t13-,16-,17-,21+,22-,23-,24-/m0/s1

Synonyms:

• (6A)-21-(Acetyloxy)-17-Hydroxy-6-Methylpregna-1,4-Diene-3,11,20-Trione
• 17,21-Dihydroxy-6a-methylpregna-1,4-diene-3,11,20-trione 21-Acetate