CAS 115365-39-4
:5-(2-chloroethyl)-2'-deoxy-3'-O-(phosphonoacetyl)uridine
Description:
5-(2-Chloroethyl)-2'-deoxy-3'-O-(phosphonoacetyl)uridine, with CAS number 115365-39-4, is a nucleoside analog that exhibits significant biological activity, particularly in antiviral and anticancer research. This compound features a uridine base modified with a chloroethyl group, which enhances its reactivity and potential for incorporation into nucleic acids. The presence of the phosphonoacetyl group contributes to its ability to inhibit nucleic acid synthesis, making it a candidate for therapeutic applications. The structural modifications impart unique properties, such as increased lipophilicity and altered metabolic stability, which can influence its pharmacokinetics and bioavailability. Additionally, the compound's mechanism of action often involves interference with viral replication processes or cellular proliferation pathways. As a result, it has garnered interest in the development of antiviral agents and chemotherapeutic drugs. However, detailed studies on its efficacy, toxicity, and specific interactions within biological systems are essential for understanding its full potential and safety profile.
Formula:C13H18ClN2O9P
InChI:InChI=1/C13H18ClN2O9P/c14-2-1-7-4-16(13(20)15-12(7)19)10-3-8(9(5-17)24-10)25-11(18)6-26(21,22)23/h4,8-10,17H,1-3,5-6H2,(H,15,19,20)(H2,21,22,23)/t8-,9+,10+/m0/s1
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Uridine, 5-(2-chloroethyl)-2'-deoxy-, 3'-(phosphonoacetate) (9CI)
CAS:Formula:C13H18ClN2O9PMolecular weight:412.7168
