CAS 1154097-71-8

IOX4

CAS: 1154097-71-8

Formula: C₁₅H₁₆N₆O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 328.3259

Ref: IN-DA01DZQ0

IOX4

CAS: 1154097-71-8

IOX4

Purity: ≥98%

Molecular weight: 328.33g/mol

Ref: 54-BUP10336

IOX-4

CAS: 1154097-71-8

Formula: C₁₅H₁₆N₆O₃

Purity: >95.0%(HPLC)(qNMR)

Color and Shape: Light yellow to Amber powder to crystal

Molecular weight: 328.33

Ref: 3B-I1267

IOX4

CAS: 1154097-71-8

Formula: C₁₅H₁₆N₆O₃

Molecular weight: 328.33

Ref: 4Z-K-031125

IOX4

CAS: 1154097-71-8

IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)

Formula: C₁₅H₁₆N₆O₃

Purity: 99.97%

Color and Shape: Solid

Molecular weight: 328.33

Ref: TM-T7880

IOX4

Controlled Product

CAS: 1154097-71-8

Applications IOX4 is a triazole based potent and selective inhibitor of hypoxia-inducible factor (HIF) prolyl-hydroxylase. It induces HIFα in cells of mouse brain. It is useful for studies that aim to validate the upregulation of HIF for treatment of cerebral diseases such as stroke.
References Chan, M., et al.: PLOS ONE, 10, e0132004/1 (2015);

Formula: C₁₅H₁₆N₆O₃

Color and Shape: Neat

Molecular weight: 328.33

Ref: TR-I737010

IOX4-d9

Controlled Product

CAS: 1154097-71-8

Formula: C₁₅D₉H₇N₆O₃

Color and Shape: Neat

Molecular weight: 337.381

Ref: TR-I737014

IOX4

CAS: 1154097-71-8

IOX4 is a benzodiazepine receptor antagonist that blocks the binding of benzodiazepines to their receptors in the central nervous system. This leads to an increase in oxygen transport and improved cancer treatment. IOX4 has been shown to inhibit the activity of G-protein coupled receptor kinase 2 (GRK2) and phospholipase C (PLC). These two proteins are critical for signal transduction, which may play a role in cancer development. IOX4 is currently being studied as a backup drug for benzodiazepine receptor antagonists with inhibitory effects on GRK2 and PLC.

Formula: C₁₅H₇D₉N₆O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 337.38 g/mol

Ref: 3D-EWB09771