The HIV envelope protein gp120 is a crucial component of the Human Immunodeficiency Virus (HIV) that facilitates the virus's entry into host cells. The specific fragment 308-331 refers to a portion of the gp120 protein, which plays a significant role in the virus's ability to bind to CD4 receptors on T-helper cells, a critical step in the infection process. This fragment is often studied for its immunogenic properties and potential as a target for vaccine development. The CAS number 115416-08-5 identifies this specific peptide fragment in chemical databases, allowing researchers to reference it accurately in studies related to HIV. Characteristics of this fragment include its peptide nature, which means it is composed of amino acids linked by peptide bonds, and its potential to elicit an immune response. Understanding the structure and function of this fragment is essential for developing therapeutic strategies against HIV, including vaccine design and monoclonal antibody development.

hiv envelope protein (gp120)*fragment 308-331

115416-08-5: The HIV envelope protein gp120 is a crucial component of the Human Immunodeficiency Virus (HIV) that facilitates the virus's entry into host cells. The specific fragment 308-331 refers to a portion of the gp120 protein, which plays a significant role in the virus's ability to bind to CD4 receptors on T-helper cells, a critical step in the infection process. This fragment is often studied for its immunogenic properties and potential as a target for vaccine development. The CAS number 115416-08-5 identifies this specific peptide fragment in chemical databases, allowing researchers to reference it accurately in studies related to HIV. Characteristics of this fragment include its peptide nature, which means it is composed of amino acids linked by peptide bonds, and its potential to elicit an immune response. Understanding the structure and function of this fragment is essential for developing therapeutic strategies against HIV, including vaccine design and monoclonal antibody development.

<p>HIV is a type of virus that causes AIDS. HIV infects the cells of the human immune system, destroying them and making the body vulnerable to infections from other types of viruses and bacteria. The gp120 protein is an envelope glycoprotein that mediates binding to the CD4 receptor on host T-helper cells and induces fusion of viral and cellular membranes. The gp120 protein has been studied using a variety of methods, including neutralizing antibody binding experiments, enzyme-linked immunosorbent assays (ELISA), Western blotting, peptide mapping, and density lipoprotein binding assays. This fragment contains residues 308-331 in a human immunodeficiency virus (HIV) type 1 gp120 protein.</p>

CAS 115416-08-5

hiv envelope protein (gp120)*fragment 308-331

HIV (gp120) Fragment (308-331)

Ref: 3D-FH109998