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CAS 115532-50-8

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tetramethylrhodamine methyl ester perchlorate

Description:
Tetramethylrhodamine methyl ester perchlorate, often abbreviated as TMRM, is a fluorescent dye commonly used in biological and chemical research. It is characterized by its vibrant red fluorescence, which makes it an excellent marker for various applications, including live-cell imaging and tracking cellular processes. The compound features a rhodamine core structure, which is known for its strong photostability and high quantum yield, allowing for effective visualization under fluorescence microscopy. TMRM is typically used to assess mitochondrial membrane potential, as it accumulates in active mitochondria, providing insights into cellular health and function. The perchlorate salt form enhances its solubility in aqueous solutions, facilitating its use in biological experiments. However, researchers must handle TMRM with care, as it can be toxic at high concentrations. Overall, tetramethylrhodamine methyl ester perchlorate is a valuable tool in the fields of biochemistry and cell biology, enabling the study of dynamic processes within living cells.
Formula:C25H25ClN2O7
InChI:InChI=1/C25H25N2O3.ClHO4/c1-26(2)16-10-12-20-22(14-16)30-23-15-17(27(3)4)11-13-21(23)24(20)18-8-6-7-9-19(18)25(28)29-5;2-1(3,4)5/h6-15H,1-5H3;(H,2,3,4,5)/q+1;/p-1
Synonyms:
  • Tetramethylrhodamine, methyl ester, perchlorate (TMRM)
  • N-{6-(dimethylamino)-9-[2-(methoxycarbonyl)phenyl]-3H-xanthen-3-ylidene}-N-methylmethanaminium perchlorate
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