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CAS 115532-52-0

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tetramethylrhodamine ethyl ester perchlorate

Description:
Tetramethylrhodamine ethyl ester perchlorate, commonly referred to as TMR, is a fluorescent dye widely used in biological and chemical research. It is characterized by its vibrant red fluorescence, which makes it an excellent marker for various applications, including microscopy and flow cytometry. The compound features a rhodamine core structure, which contributes to its strong light absorption and emission properties. TMR is typically soluble in organic solvents and exhibits stability under a range of conditions, although it can be sensitive to photobleaching when exposed to intense light. The perchlorate salt form enhances its solubility in aqueous solutions, making it suitable for biological assays. Additionally, TMR can be used for labeling biomolecules, allowing researchers to track cellular processes and interactions. Its high quantum yield and low background fluorescence further enhance its utility in experimental settings. However, as with many chemical substances, appropriate safety measures should be taken when handling TMR, as it may pose risks if ingested or inhaled.
Formula:C26H27ClN2O7
InChI:InChI=1S/C26H27N2O3.ClHO4/c1-6-30-26(29)20-10-8-7-9-19(20)25-21-13-11-17(27(2)3)15-23(21)31-24-16-18(28(4)5)12-14-22(24)25;2-1(3,4)5/h7-16H,6H2,1-5H3;(H,2,3,4,5)/q+1;/p-1
InChI key:InChIKey=NBAOBNBFGNQAEJ-UHFFFAOYSA-M
SMILES:Cl(=O)(=O)(=O)[O-].C(OCC)(=O)C1=C(C=2C3=C([O+]=C4C2C=CC(N(C)C)=C4)C=C(N(C)C)C=C3)C=CC=C1
Synonyms:
  • T 669
  • Tetramethylrhodamine, ethyl ester, perchlorate (TMRE)
  • Xanthylium, 3,6-bis(dimethylamino)-9-[2-(ethoxycarbonyl)phenyl]-, perchlorate
  • Xanthylium, 3,6-bis(dimethylamino)-9-[2-(ethoxycarbonyl)phenyl]-, perchlorate (1:1)
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