CAS 115538-85-7

7α-Hydroxy-3-oxo-4-cholestenoic acid

Description:

7α-Hydroxy-3-oxo-4-cholestenoic acid, with the CAS number 115538-85-7, is a steroid compound that plays a significant role in the metabolism of cholesterol and bile acids. It is characterized by a hydroxyl group at the 7α position and a keto group at the 3 position of the steroid nucleus, which contributes to its biological activity. This compound is involved in various biochemical pathways, particularly in the regulation of cholesterol homeostasis and the synthesis of bile acids. Its structure features a steroid backbone, which is typical of many biologically active molecules, and it exhibits hydrophobic properties due to its steroidal nature. The presence of functional groups such as hydroxyl and keto enhances its solubility in polar solvents, influencing its interaction with biological membranes and enzymes. Research indicates that it may have implications in metabolic disorders and could serve as a potential biomarker or therapeutic target in cholesterol-related diseases.

Formula: C₂₇H₄₂O₄

InChI: InChI=1S/C27H42O4/c1-16(6-5-7-17(2)25(30)31)20-8-9-21-24-22(11-13-27(20,21)4)26(3)12-10-19(28)14-18(26)15-23(24)29/h14,16-17,20-24,29H,5-13,15H2,1-4H3,(H,30,31)/t16-,17?,20-,21+,22+,23-,24+,26+,27-/m1/s1

InChI key: InChIKey=SATGKQGFUDXGAX-MYWFJNCASA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(C[C@H]3O)=CC(=O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCCC(C(O)=O)C)C)[H])[H]

Synonyms:

• (7Alpha)-7-Hydroxy-3-Oxocholest-4-En-26-Oic Acid
• (7α)-7-Hydroxy-3-oxocholest-4-en-26-oic acid
• 7 Alpha-Hydroxy-3-Oxo-4-Cholestenoic Acid
• 7α-Hydroxy-3-oxo-4-cholestenoic acid
• 7α-Hydroxy-3-oxocholest-4-en-26-oic acid
• Cholest-4-en-26-oic acid, 7-hydroxy-3-oxo-, (7α)-

Cholest-4-en-26-oic acid, 7-hydroxy-3-oxo-, (7α)-

CAS: 115538-85-7

Formula: C₂₇H₄₂O₄

Color and Shape: Solid

Molecular weight: 430.62

Ref: IN-DA000G4M

7a-hydroxy-3-oxocholest-4-en-26-oic acid

CAS: 115538-85-7

Formula: C27H42O4

Purity: None

Molecular weight: 430.62

Ref: 48-65-1110

7-alfa-Hydroxy-3-oxo-4-Cholestenoic Acid

CAS: 115538-85-7

Formula: C₂₇H₄₂O₄

Molecular weight: 430.63

Ref: 4Z-C-53112

7-Hydroxy-3-oxo-Cholest-4-en-26-oic Acid

Controlled Product

CAS: 115538-85-7

Applications 7-Hydroxy-3-oxo-Cholest-4-en-26-oic Acid is a compound that indicates the permeability of the blood-brain barrier. It is a metabolite of 27-OHC.
References Saeed, A. et al.: J. Lipid. Res., 55, 313 (2014); Meaney, S. et al.: J. Lipid. Res., 48, 944 (2007);

Formula: C₂₇H₄₂O₄

Color and Shape: Neat

Molecular weight: 430.62

Ref: TR-H949660

7-Hydroxy-3-oxo-Cholest-4-en-26-oic Acid-d3

Controlled Product

CAS: 115538-85-7

Formula: C₂₇D₃H₃₉O₄

Color and Shape: Neat

Molecular weight: 433.639

Ref: TR-H949662

7-Hydroxy-3-oxo-cholest-4-en-26-oic acid

Controlled Product

CAS: 115538-85-7

7-Hydroxy-3-oxo-cholest-4-en-26-oic acid is a potent inhibitor of protein kinase activity and has been shown to induce apoptosis in cancer cells. This analog is derived from Chinese medicinal plants and has been found in human urine. It has demonstrated anticancer activity by inhibiting cell cycle progression and inducing apoptosis in tumor cells. Additionally, 7-Hydroxy-3-oxo-cholest-4-en-26-oic acid has been identified as a potential therapeutic target for cancer treatment due to its ability to inhibit the growth of cancer cells. Its unique characteristics make it an effective inhibitor for proteins involved in cancer development and progression.

Formula: C₂₇H₄₂O₄

Purity: Min. 95%

Molecular weight: 430.6 g/mol

Ref: 3D-QEA53885