CAS 115655-86-2

actinoplanone A

Description:

Actinoplanone A is a natural product belonging to the class of polyketides, specifically known for its antibiotic properties. It is produced by the actinobacterium Actinoplanes sp. and exhibits a complex molecular structure characterized by multiple functional groups, including ketones and hydroxyl groups. This compound is notable for its potential applications in medicinal chemistry, particularly in the development of new antimicrobial agents. Actinoplanone A has been studied for its mechanism of action, which involves inhibiting bacterial cell wall synthesis, making it effective against various Gram-positive bacteria. Its unique structural features contribute to its biological activity, and ongoing research aims to explore its full therapeutic potential and to understand its biosynthetic pathways. As with many natural products, the extraction and purification of actinoplanone A can be challenging, but advancements in analytical techniques continue to enhance our understanding of this compound and its derivatives.

Formula: C₂₈H₂₅ClN₂O₁₀

Synonyms:

• Actinoplanone A
• (1S-(1alpha,3alpha,4beta,8aalpha))-13-Amino-11-chloro-3,4,8a,13-tetrahydro-3,15,16-trihydroxy-1,4-dimethoxy-12-methyl-1H-xantheno(4',3',2':4,5)(1,3)benzodioxino(7,6-g)isoquinoline-14,17(2H,9H)-dione
• 13-Amino-11-chloro-3,4,8a,13-tetrahydro-3,15,16-trihydroxy-1,4-dimethoxy-12-methyl-1H-xantheno(4',3',2':4,5)(1,3)benzodioxino(7,6-g)isoquinoline-14,17(2H,9H)-dione (1S-(1alpha,3alpha,4beta,8aalpha))-
• 1H-Xantheno(4',3',2':4,5)(1,3)benzodioxino(7,6-g)isoquinoline-14,17(2H,9H)-dione, 13-amino-11-chloro-3,4,8a,13-tetrahydro-3,15,16-trihydroxy-1,4-dimethoxy-12-methyl-, (1S-(1alpha,3alpha,4beta,8aalpha))-
• Actonoplanone
• Actonoplanone A
• 1H-Xantheno[4',3',2':4,5][1,3]benzodioxino[7,6-g]isoquinoline-14,17(2H,9H)-dione, 13-amino-11-chloro-3,4,8a,13-tetrahydro-3,15,16-trihydroxy-1,4-dimethoxy-12-methyl-, (1S,3R,4S,8aR)- (9CI)

Actinoplanone A

CAS: 115655-86-2

Actinoplanone A is a polycyclic flavonoid antibiotic (antibiotic) with potent antibacterial activity against bacteria and Magnaporthe oryzae. It exhibits cytotoxicity against various tumor cells and inhibits DNA synthesis.

Formula: C₂₈H₂₅ClN₂O₁₀

Color and Shape: Solid

Molecular weight: 584.959

Ref: TM-TN9052