CAS 115695-30-2

pTH-Related Protein (7-34) amide (human, rat)

Description:

pTH-Related Protein (7-34) amide, associated with the CAS number 115695-30-2, is a synthetic peptide that is a fragment of the parathyroid hormone-related peptide (PTHrP). This peptide is characterized by its role in various physiological processes, including calcium homeostasis and bone metabolism. It is particularly noted for its involvement in the regulation of bone formation and resorption. The amide form indicates that the C-terminus of the peptide is modified to enhance stability and bioactivity. This peptide is often used in research to study the mechanisms of action of PTHrP and its receptor interactions, as well as its potential therapeutic applications in conditions such as osteoporosis and cancer-related bone diseases. The structural characteristics include a specific sequence of amino acids that confer its biological activity, and it is typically synthesized using solid-phase peptide synthesis techniques. Overall, pTH-Related Protein (7-34) amide serves as a valuable tool in both basic and applied biomedical research.

Formula: C₁₅₃H₂₄₇N₄O₃₇

Synonyms:

• H-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2

pTH-Related Protein (7-34) amide (human, mouse, rat)

CAS: 115695-30-2

pTHrP (7-34) amide is a potent antagonist of the effects of pTH-related protein (1-34) in vitro and in vivo.

Formula: C₁₅₃H₂₄₇N₄₉O₃₇

Purity: 94.0%

Color and Shape: White Lyophilisate

Molecular weight: 3364.95

Ref: 01-4016931

PTH-rP (Human, 7-34 Amide)

CAS: 115695-30-2

PTH-rP (Human, 7-34 Amide), sourced from rat, and mouse and available as a 0.5mg vial, is an antagnoist of the A Parathyroid Hormone related Peptide (PTH-rP). PTH-rP is a peptide that belongs to the group of activators. PTH-rP has been shown to activate phospholipase C, which leads to increased intracellular calcium levels and activation of protein kinase C. PTH-rP also binds to the receptor for parathyroid hormone (PTH), and activates it by binding to its extracellular domain. This receptor is found in most cells in the body, including those in bone, kidney, gut and brain. The ligand-receptor interaction causes an increase in intracellular calcium levels that triggers a cascade of downstream effects on cell metabolism and gene expression.

Formula: C₁₅₃H₂₄₇N₄₉O₃₇

Purity: Min. 95%

Molecular weight: 3,364.9 g/mol

Ref: 3D-PTH-4215-V

pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt

CAS: 115695-30-2

Please enquire for more information about pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₅₃H₂₄₇N₄₉O₃₇

Purity: Min. 95%

Molecular weight: 3,364.91 g/mol

Ref: 3D-FP110381