CAS 115722-78-6

N-Acetoxy-IQ

Description:

N-Acetoxy-IQ, with the CAS number 115722-78-6, is a chemical compound that belongs to the class of acetoxy derivatives of the aminoquinoline family. It is characterized by the presence of an acetoxy group (-OCOCH3) attached to the nitrogen-containing heterocyclic structure of IQ (IQ refers to 2-amino-3-methylimidazo[4,5-f]quinoline). This compound is of interest in the field of medicinal chemistry and toxicology due to its potential biological activities and implications in mutagenicity and carcinogenicity studies. N-Acetoxy-IQ is typically a solid at room temperature and may exhibit solubility in organic solvents. Its reactivity is influenced by the acetoxy group, which can undergo hydrolysis to form the corresponding amine and acetic acid. The compound's structure allows it to interact with biological macromolecules, which is crucial for understanding its mechanism of action and potential health effects. As with many chemical substances, handling should be done with care, considering its potential biological effects.

Formula: C₁₃H₁₂N₄O₂

InChI: InChI=1/C13H12N4O2/c1-8(18)19-16-13-15-12-9-4-3-7-14-10(9)5-6-11(12)17(13)2/h3-7H,1-2H3,(H,15,16)

Synonyms:

• N-Acetoxy-IQ
• Acetic acid, (3-methyl-3H-imidazo[4,5-f]quinolin-2-yl)azanyl ester
• 2H-Imidazo(4,5-f)quinolin-2-one, 1,3-dihydro-3-methyl-, O-acetyloxime
• 1-{[(3-methyl-3H-imidazo[4,5-f]quinolin-2-yl)amino]oxy}ethanone
• 1,3-Dihydro-3-methyl-2H-imidazo(4,5-f)quinolin-2-one O-acetyloxime

N-Acetoxy-IQ

CAS: 115722-78-6

N-Acetoxy-IQ is a DNA alkylating agent that can covalently bind to DNA, specifically targeting guanine residues. By forming DNA adducts, N-Acetoxy-IQ exerts mutagenic and carcinogenic effects. It is a promising compound for cancer research.

Formula: C₁₃H₁₂N₄O₂

Color and Shape: Solid

Molecular weight: 256.26

Ref: TM-TN10599