CAS 115730-97-7
:Quinidine 1Oxide
Description:
Quinidine 1-Oxide is a chemical compound that is a derivative of quinidine, which is an alkaloid used primarily as an antiarrhythmic agent. This substance is characterized by its structural modification, where an oxygen atom is incorporated into the quinidine framework, resulting in altered pharmacological properties. Quinidine 1-Oxide exhibits a chiral nature, possessing stereoisomers that can influence its biological activity and interactions. It is typically found in a crystalline form and is soluble in organic solvents, with limited solubility in water. The compound is of interest in medicinal chemistry due to its potential effects on cardiac rhythm and its role in drug metabolism, particularly as a metabolite of quinidine. Its mechanism of action involves the blockade of sodium channels, which can affect cardiac conduction. As with many quinine derivatives, it may also exhibit antimalarial properties. Safety and handling precautions are essential, as with all chemical substances, due to potential toxicity and side effects associated with its use.
Formula:C20H24N2O3
InChI:InChI=1/C20H24N2O3/c1-3-13-12-21-8-6-14(13)10-19(21)20(23)16-7-9-22(24)18-5-4-15(25-2)11-17(16)18/h3-5,7,9,11,13-14,19-20,23H,1,6,8,10,12H2,2H3/t13-,14?,19+,20-/m0/s1
Synonyms:- 6'-Methoxy-cinchonan-9-ol 1'-Oxide
- Icq 17
- Quinidine 1'-N-oxide
- Quinidine 1'-oxide
- Quinidine ar-N-oxide
- Quinidine N'-oxide
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Found 2 products.
Quinidine 1’-Oxide
CAS:Controlled Product<p>Applications A metabolite of Quinidine.<br>References Small, D.L., J. Chem. Med., 22,1014 (1979), Guentert, T.W., et al.: Eur. J. Drug Metab. Pharmacokinet., 7, 31 (1982), Chang, Y.F., et al.: Neurochem. Res., 13, 455 (1988),<br></p>Formula:C20H24N2O3Color and Shape:NeatMolecular weight:340.42
