CAS 1158-10-7

3,5-Diiodothyropropionic acid

Description:

3,5-Diiodothyropropionic acid, with the CAS number 1158-10-7, is a synthetic derivative of thyroxine, a hormone produced by the thyroid gland. This compound is characterized by the presence of two iodine atoms at the 3 and 5 positions of the thyronine structure, which significantly influences its biological activity and potency. It is a white to off-white crystalline solid that is soluble in water and organic solvents, reflecting its polar nature due to the carboxylic acid functional group. The compound is primarily studied for its potential effects on metabolism and thyroid function, often in the context of research on thyroid-related disorders. Its structural modifications compared to thyroxine may lead to variations in its pharmacological properties, making it a subject of interest in medicinal chemistry. Additionally, 3,5-Diiodothyropropionic acid may exhibit antioxidant properties and influence lipid metabolism, although further studies are necessary to fully elucidate its mechanisms of action and therapeutic potential.

Formula: C₁₅H₁₂I₂O₄

InChI: InChI=1S/C15H12I2O4/c16-12-7-9(1-6-14(19)20)8-13(17)15(12)21-11-4-2-10(18)3-5-11/h2-5,7-8,18H,1,6H2,(H,19,20)

InChI key: InChIKey=WONYMNWUJVKVII-UHFFFAOYSA-N

SMILES: O(C1=C(I)C=C(CCC(O)=O)C=C1I)C2=CC=C(O)C=C2

Synonyms:

• 3,5-Diiodothyropropionic acid
• 3,5-Ditpa
• 3-[4-(4-Hydroxyphenoxy)-3,5-Diiodophenyl]Propanoic Acid
• 4-(4-Hydroxyphenoxy)-3,5-diiodobenzenepropanoic acid
• Benzenepropanoic acid, 4-(4-hydroxyphenoxy)-3,5-diiodo-
• Dipro
• Ditpa
• Hydrocinnamic acid, 4-(p-hydroxyphenoxy)-3,5-diiodo-

3,5-Diiodothyropropionic acid

CAS: 1158-10-7

3,5-Diiodothyropropionic acid: thyroid hormone analog, boosts α-myosin mRNA, binds TRα1 & TRβ1 (Ka: 2.40/M, 4.06/M).

Formula: C₁₅H₁₂I₂O₄

Purity: 98.42%

Color and Shape: Solid

Molecular weight: 510.06

Ref: TM-T13492

3-[4-(4-Hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid

CAS: 1158-10-7

Formula: C₁₅H₁₂I₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 510.0623

Ref: IN-DA000GWD

3,5-Diiodothyropropionic acid

CAS: 1158-10-7

3,5-Diiodothyropropionic acid

Purity: ≥98%

Molecular weight: 510.06g/mol

Ref: 54-BUP10297

Levothyroxine Impurity 59

CAS: 1158-10-7

Formula: C₁₅H₁₂I₂O₄

Molecular weight: 510.07

Ref: 4Z-L-4683

3,5-Diiodothyropropionic Acid

Controlled Product

CAS: 1158-10-7

Applications 3,5-Diiodothyropropionic acid is an ionotropic analog of L-thyroxine.

Formula: C₁₅H₁₂I₂O₄

Color and Shape: Neat

Molecular weight: 510.06

Ref: TR-D466068