CAS 1158083-48-7

Boceprevir Metabolite M4-d9 Methyl Ester

Controlled Product

CAS: 1158083-48-7

Applications Protected Boceprevir Metabolite M4-d9 (B674522). A labelled metabolite of the Hepatitis C virus NS3 serine protease inhibitor Boceprevir (B675500). It is a COVID19-related research product.
References Venkatraman, S. et al.: J. Med. Chem., 49, 6074 (2006); Morgan, A.J, et al.: J. Lab. Cpd. Radiopharmac., 54, 613 (2011);

Formula: C₂₀₂H₉H₂₆N₃O₄

Color and Shape: Neat

Molecular weight: 390.57

Ref: TR-B674517

Boceprevir metabolite M4-d9 methyl ester

CAS: 1158083-48-7

Boceprevir metabolite M4-d9 methyl ester is a peptide that is used as a research tool for studying protein interactions, receptor pharmacology, and ion channel activity. It has been shown to inhibit the hepatitis C virus (HCV) NS3 protease by binding to the active site of the enzyme. Boceprevir metabolite M4-d9 methyl ester binds to the HCV NS3 protease with a Kd of 1.2 nM and an IC50 of 2.6 μM in vitro. This peptide also inhibits HIV-1 entry into host cells by competitively inhibiting gp41 binding to CD4 or CCR5 receptors, thereby preventing viral fusion with host cell membranes.

Formula: C₂₀H₃₅N₃O₄

Purity: Min. 95%

Molecular weight: 390.6 g/mol

Ref: 3D-IWB08348