Suc-Gly-Pro-pNA, also known as Succinyl-Glycyl-Prolyl-p-Nitroanilide, is a synthetic peptide substrate commonly used in biochemical assays, particularly for the detection of proteolytic enzymes. This compound features a succinyl group, which enhances its solubility and stability, and is composed of three amino acids: glycine, proline, and a p-nitroanilide moiety that serves as a chromogenic indicator. Upon cleavage by specific proteases, Suc-Gly-Pro-pNA releases p-nitroaniline, which can be quantitatively measured due to its distinct color change, making it useful in enzyme kinetics studies. The compound is typically soluble in aqueous solutions and exhibits stability under standard laboratory conditions. Its utility in enzyme assays makes it a valuable tool in both research and clinical diagnostics, particularly in the study of proteases involved in various biological processes. As with any chemical substance, proper handling and safety protocols should be observed to mitigate any potential hazards.

Suc-Gly-Pro-pNA

115846-45-2: Suc-Gly-Pro-pNA, also known as Succinyl-Glycyl-Prolyl-p-Nitroanilide, is a synthetic peptide substrate commonly used in biochemical assays, particularly for the detection of proteolytic enzymes. This compound features a succinyl group, which enhances its solubility and stability, and is composed of three amino acids: glycine, proline, and a p-nitroanilide moiety that serves as a chromogenic indicator. Upon cleavage by specific proteases, Suc-Gly-Pro-pNA releases p-nitroaniline, which can be quantitatively measured due to its distinct color change, making it useful in enzyme kinetics studies. The compound is typically soluble in aqueous solutions and exhibits stability under standard laboratory conditions. Its utility in enzyme assays makes it a valuable tool in both research and clinical diagnostics, particularly in the study of proteases involved in various biological processes. As with any chemical substance, proper handling and safety protocols should be observed to mitigate any potential hazards.

<p>Suc-Gly-Pro-pNA is a proteolytic enzyme that hydrolyzes proteins. It has been shown to have potential for use as an anti-inflammatory agent. Suc-Gly-Pro-pNA has high proteolytic activity and can cleave peptide hormones such as angiotensin II and vasopressin. It also has thermal stability, and can tolerate high concentrations of salt and heat, making it suitable for therapeutic purposes. Suc-Gly-Pro-pNA binds to peptides with carboxy terminal residues by substrate binding, which may be the reason for its high degree of specificity. This enzyme is expressed in the cytosol and extracellular environment.</p>

CAS 115846-45-2

Suc-Gly-Pro-pNA

Suc-Gly-Pro-pNA

Ref: 3D-FS110760

Suc-Gly-Pro-pNA

Ref: 01-4014710