CAS 115899-40-6

Uridine, 2'-deoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]-

Description:

Uridine, 2'-deoxy-5-[3-[(trifluoroacetyl)amino]-1-propynyl]- is a modified nucleoside that features a deoxyribose sugar moiety and a trifluoroacetyl group attached to a propynyl chain at the 5-position of the uridine base. This compound is characterized by its structural modifications that enhance its stability and bioactivity compared to natural nucleosides. The presence of the trifluoroacetyl group contributes to its lipophilicity, potentially influencing its cellular uptake and interaction with biological targets. The propynyl moiety may also impart unique reactivity or binding properties, making it of interest in medicinal chemistry and drug development. As a nucleoside analog, it may exhibit antiviral or anticancer properties, although specific biological activities would depend on further empirical studies. Overall, this compound represents a class of nucleoside derivatives that are valuable in research and therapeutic applications, particularly in the context of nucleic acid metabolism and modulation.

Formula: C₁₄H₁₄F₃N₃O₆

Uridine, 2'-deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propyn-1-yl]-

CAS: 115899-40-6

Formula: C₁₄H₁₄F₃N₃O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 377.2727

Ref: IN-DA000H24

TFA-ap-dU

CAS: 115899-40-6

TFA-ap-dU

Purity: 98%

Molecular weight: 377.27g/mol

Ref: 54-PC1001056

TFA-ap-dU

CAS: 115899-40-6

Formula: C₁₄H₁₄F₃N₃O₆

Purity: 98%

Molecular weight: 377.276

Ref: 10-F463470

2'-Deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propyn-1-yl]uridine

Controlled Product

CAS: 115899-40-6

Applications 2'-Deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propyn-1-yl]uridine is an intermediate in the synthesis of fluorescent labeling compounds of cyclooctyne-modified deoxyuridine triphosphates in DNA.
References Ren, X.M., et al.: Bioorg. Med. Chem., 22, 4384 (2014); Borsenberger, V., et al.: Org. Biomolec. Chem., 7, 3826 (2009);

Formula: C₁₄H₁₄F₃N₃O₆

Color and Shape: Neat

Molecular weight: 377.27

Ref: TR-D282515

TFA-ap-dU

CAS: 115899-40-6

TFA-ap-dU is a modified, ribonucleosides that are used in DNA synthesis. The polymerase chain reaction (PCR) technique can be used to generate a large number of copies of a specific sequence of nucleotides from the original DNA template. This product is used for antiviral and anticancer research. TFA-ap-dU has been shown to be effective against Hepatitis B virus and Human Immunodeficiency Virus (HIV). It is also an activator of DNA and RNA synthesis.

Formula: C₁₄H₁₄F₃N₃O₆

Purity: Min. 95%

Molecular weight: 377.27 g/mol

Ref: 3D-NT57551