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CAS 1159-15-5

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Tos-Arg-OH

Description:
Tos-Arg-OH, also known as Tosyl-Arginine, is a chemical compound characterized by the presence of a tosyl group (a sulfonyl group derived from toluenesulfonic acid) attached to the amino acid arginine. This compound is typically used in biochemical and pharmaceutical applications, particularly in peptide synthesis and as a protecting group for the amino group of arginine. The tosyl group enhances the stability and reactivity of the arginine residue, making it useful in various synthetic pathways. Tos-Arg-OH is soluble in polar solvents, which facilitates its use in aqueous environments. Its structure includes a guanidinium group, characteristic of arginine, which contributes to its basicity and potential interactions in biological systems. The compound is often utilized in research settings, particularly in studies involving protein interactions and modifications. Safety data should be consulted for handling, as with any chemical substance, to ensure proper laboratory practices are followed.
Formula:C13H20N4O4S
InChI:InChI=1/C13H20N4O4S/c1-9-4-6-10(7-5-9)22(20,21)17-11(12(18)19)3-2-8-16-13(14)15/h4-7,11,17H,2-3,8H2,1H3,(H,18,19)(H4,14,15,16)
SMILES:Cc1ccc(cc1)S(=O)(=O)NC(CCCNC(=N)N)C(=O)O
Synonyms:
  • N-Tosyl-L-arginine
  • N~5~-(diaminomethylidene)-N~2~-[(4-methylphenyl)sulfonyl]-L-ornithine
  • N~5~-(diaminomethylidene)-N~2~-[(4-methylphenyl)sulfonyl]ornithine
  • N-p-Tosyl-L-arginine
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