CAS 115918-60-0

L-SERINE 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE

Description:

L-Serine 7-amido-4-methylcoumarin hydrochloride is a synthetic compound that serves as a fluorescent substrate for serine proteases, enzymes that cleave peptide bonds in proteins. This compound features a coumarin moiety, which is known for its fluorescent properties, making it useful in biochemical assays and research applications. The presence of the L-serine amino acid component contributes to its specificity for serine proteases, allowing for the study of enzyme kinetics and activity. As a hydrochloride salt, it is typically more soluble in water, facilitating its use in various biological experiments. The compound is characterized by its ability to emit fluorescence upon enzymatic cleavage, providing a visual or measurable signal that can be quantified. Its applications extend to fields such as molecular biology, biochemistry, and pharmacology, where it aids in the understanding of protease functions and interactions. Proper handling and storage conditions are essential to maintain its stability and efficacy in experimental settings.

Formula: C₁₃H₁₅N₂O₄

InChI: InChI=1/C13H14N2O4/c1-7-4-12(17)19-11-5-8(2-3-9(7)11)15-13(18)10(14)6-16/h2-5,10,16H,6,14H2,1H3,(H,15,18)/p+1/t10-/m0/s1

Synonyms:

• Serine-Amc Hcl
• L-Serine-7-Amido-4-Methylcoumarin Hydrochloride Hydrate
• H-Ser-Amc Hcl
• L-Serine-7-Amido-4-Methylcoumarin Hydrochloride Hydrate 98%
• l-serine-7-amido-4-methylcoumarinHClhydrate
• H-L-Ser-AMC*HCl
• N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-serinamide hydrochloride
• (2S)-3-hydroxy-1-[(4-methyl-2-oxo-2H-chromen-7-yl)amino]-1-oxopropan-2-aminium

L-Serine 7-amido-4-methylcoumarin hydrochloride

CAS: 115918-60-0

L-Serine 7-amido-4-methylcoumarin hydrochloride is a fluorogenic peptide substrate for peptidases. This AMC peptide substrate is normally used to rapidly profile the N-terminal specificity of proteases.

Formula: C₁₃H₁₅ClN₂O₄

Molecular weight: 298.72 g/mol

Ref: 3D-S-2700