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CAS 115926-52-8

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Phosphatidylinositol 3-kinase family

Description:
Phosphatidylinositol 3-kinase (PI3K) family refers to a group of enzymes involved in cellular signaling pathways, particularly those regulating growth, proliferation, and survival. The specific CAS number 115926-52-8 corresponds to a compound that acts as an inhibitor of PI3K, which plays a crucial role in various cellular processes by phosphorylating phosphatidylinositol lipids. These enzymes are integral to the phosphoinositide signaling pathway, influencing cellular functions such as metabolism, cell cycle progression, and apoptosis. The inhibition of PI3K has significant implications in cancer research, as aberrant PI3K signaling is often associated with tumorigenesis. Characteristics of PI3K inhibitors typically include their ability to selectively target specific isoforms of the enzyme, thus minimizing off-target effects. Additionally, these compounds may exhibit varying degrees of potency and selectivity, which are critical for their therapeutic efficacy. Overall, the PI3K family represents a vital area of study in pharmacology and biochemistry, particularly in the context of developing targeted cancer therapies.
Formula:Unspecified
Synonyms:
  • Phosphatidylinositol 3-kinase family
  • Phosphoinositide 3′-kinase
  • Phosphatidylinositol 3′-kinase
  • Kinase (phosphorylating), phosphatidylinositol 3-
  • Phosphoinositide 3-kinase
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Found 1 products.
  • Pi3K (P110-β/P85-β), active, His tagged human

    CAS:
    <p>Pi3K (P110-β/P85-β), active, His tagged human is a high purity, recombinant protein. Pi3K (P110-β/P85-β) is an activator of the phosphatidylinositol 3-kinase (PI3K) enzyme. It has been shown to be involved in many cellular processes, including cell proliferation and differentiation, as well as in the regulation of insulin secretion. This protein also interacts with other proteins such as PLCγ1, PDCD4, and PTEN.</p>
    Purity:Min. 95%

    Ref: 3D-QEA92652

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