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CAS 115956-13-3

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dolasetron mesylate

Description:
Dolasetron mesylate is a pharmaceutical compound primarily used as an antiemetic, particularly for the prevention of nausea and vomiting associated with chemotherapy and surgery. It is a selective serotonin 5-HT3 receptor antagonist, which works by blocking the action of serotonin, a neurotransmitter that can trigger nausea. The substance is typically administered intravenously or orally and is known for its rapid onset of action. Dolasetron mesylate is characterized by its solubility in water, which facilitates its formulation in injectable forms. The compound has a molecular formula that reflects its complex structure, including a mesylate group that enhances its pharmacological properties. Common side effects may include headache, dizziness, and gastrointestinal disturbances. Due to its mechanism of action, dolasetron mesylate is particularly effective in managing acute nausea and vomiting, making it a valuable option in clinical settings. As with any medication, it is essential to consider contraindications and potential interactions with other drugs when prescribing dolasetron mesylate.
Formula:C20H26N2O7S
InChI:InChI=1/C19H20N2O3.CH4O3S.H2O/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17;1-5(2,3)4;/h1-4,9,11-14,20H,5-8,10H2;1H3,(H,2,3,4);1H2/t11-,12+,13-,14-;;
InChI key:InChIKey=PSGRLCOSIXJUAL-ARYLMGLANA-N
SMILES:O(C(=O)C=1C=2C(NC1)=CC=CC2)[C@@H]3C[C@]4([N@]5[C@](CC(C4)C(=O)C5)(C3)[H])[H].S(C)(=O)(=O)O
Synonyms:
  • (2Alpha,6Alpha,8Alpha,9Abeta)-Octahydro-3-Oxo-2,6-Methano-2H-Quinolizin-8-Yl-1H-Indole-3-Carboxylate Monomethanesulfonate
  • (2R,6R,8R,9aS)-3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1)
  • (6R)-3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1)
  • 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, (2α,6α,8α,9aβ)-, monomethanesulfonate
  • 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer, methanesulfonate (1:1)
  • 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer, monomethanesulfonate
  • 2,6-Methano-2H-quinolizine, 1H-indole-3-carboxylic acid deriv.
  • 3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1)
  • Anxemet
  • Anzemet
  • See more synonyms
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