CAS 115956-13-3: dolasetron mesylate

Description: Dolasetron mesylate is a pharmaceutical compound primarily used as an antiemetic, particularly for the prevention of nausea and vomiting associated with chemotherapy and surgery. It is a selective serotonin 5-HT3 receptor antagonist, which works by blocking the action of serotonin, a neurotransmitter that can trigger nausea. The substance is typically administered intravenously or orally and is known for its rapid onset of action. Dolasetron mesylate is characterized by its solubility in water, which facilitates its formulation in injectable forms. The compound has a molecular formula that reflects its complex structure, including a mesylate group that enhances its pharmacological properties. Common side effects may include headache, dizziness, and gastrointestinal disturbances. Due to its mechanism of action, dolasetron mesylate is particularly effective in managing acute nausea and vomiting, making it a valuable option in clinical settings. As with any medication, it is essential to consider contraindications and potential interactions with other drugs when prescribing dolasetron mesylate.

Formula: C₁₉H₂₀N₂O₃·CH₄O₃S

InChI: InChI=1/C19H20N2O3.CH4O3S/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17;1-5(2,3)4/h1-4,9,11-14,20H,5-8,10H2;1H3,(H,2,3,4)/t11?,12-,13+,14+;

InChI key: InChIKey=PSGRLCOSIXJUAL-ARYLMGLANA-N

SMILES: O=C(OC1CC2N3CC(=O)C(C2)CC3C1)C4=CNC=5C=CC=CC54.O=S(=O)(O)C

Synonyms:

• (2Alpha,6Alpha,8Alpha,9Abeta)-Octahydro-3-Oxo-2,6-Methano-2H-Quinolizin-8-Yl-1H-Indole-3-Carboxylate Monomethanesulfonate
• (2R,6R,8R,9aS)-3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1)
• (6R)-3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1)
• 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, (2α,6α,8α,9aβ)-, monomethanesulfonate
• 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer, methanesulfonate (1:1)
• 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer, monomethanesulfonate
• 2,6-Methano-2H-quinolizine, 1H-indole-3-carboxylic acid deriv.
• 3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate methanesulfonate (1:1)
• Anxemet
• Anzemet
• Mdl 73147Ef

1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer, methanesulfonate (1:1)

CAS: 115956-13-3

• Formula: C₂₀H₂₄N₂O₆S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 420.4793599999998

Dolasetron mesylate hydrate

CAS: 115956-13-3

• Formula: C₁₉H₂₀N₂O₃·CH₄O₃S·xH₂O
• Molecular weight: 420.48 (anhydrous)

Dolasetron Mesylate Monohydrate

CAS: 115956-13-3878143-33-0

• Formula: C₁₉H₂₀N₂O₃·CH₄O₃S·H₂O
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 438.50

Dolasetron mesylate

CAS: 115956-13-3

Serotonin receptor 5-HT3 antagonist

• Formula: C₁₉H₂₀N₂O₃·CH₄O₃S
• Purity: Min. 95%
• Color and Shape: White Powder

Dolasetron Mesylate

CAS: 115956-13-3

Dolasetron Mesylate (MDL-73147EF) is an antagonist of the 5-HT3 receptor and can be used in …

• Formula: C₂₀H₂₄N₂O₆S
• Purity: 100%
• Color and Shape: White Powder
• Molecular weight: 420.48