CAS 1159600-41-5

(1,1-Dioxido-4-thiomorpholinyl)[6-[[3-(4-fluorophenyl)-5-methyl-4-isoxazolyl]methoxy]-3-pyridinyl]methanone

Description:

The chemical substance known as (1,1-Dioxido-4-thiomorpholinyl)[6-[[3-(4-fluorophenyl)-5-methyl-4-isoxazolyl]methoxy]-3-pyridinyl]methanone, with CAS number 1159600-41-5, is characterized by its complex molecular structure, which includes a thiomorpholine ring and multiple aromatic and heterocyclic components. This compound features a dioxido group, which contributes to its potential reactivity and solubility properties. The presence of a fluorophenyl group suggests possible applications in medicinal chemistry, particularly in the development of pharmaceuticals, as fluorinated compounds often exhibit enhanced biological activity and metabolic stability. The isoxazole and pyridine moieties may also impart specific pharmacological properties, making this compound of interest in drug discovery. Its synthesis and characterization would typically involve advanced organic chemistry techniques, and its behavior in biological systems would be evaluated through various assays to determine efficacy and safety profiles. Overall, this compound exemplifies the intricate design often seen in modern medicinal chemistry aimed at targeting specific biological pathways.

Formula: C₂₁H₂₀FN₃O₅S

InChI: InChI=1S/C21H20FN3O5S/c1-14-18(20(24-30-14)15-2-5-17(22)6-3-15)13-29-19-7-4-16(12-23-19)21(26)25-8-10-31(27,28)11-9-25/h2-7,12H,8-11,13H2,1H3

InChI key: InChIKey=VCGRFBXVSFAGGA-UHFFFAOYSA-N

SMILES: C(OC1=CC=C(C(=O)N2CCS(=O)(=O)CC2)C=N1)C=3C(=NOC3C)C4=CC=C(F)C=C4

Synonyms:

• RG 1662
• (1,1-Dioxo-4-thiomorpholinyl)[6-[[3-(4-fluorophenyl)-5-methylisoxazol-4-yl]methoxy]pyridin-3-yl]methanone
• Basmisanil
• Methanone, (1,1-dioxido-4-thiomorpholinyl)[6-[[3-(4-fluorophenyl)-5-methyl-4-isoxazolyl]methoxy]-3-pyridinyl]-
• (1,1-Dioxido-4-thiomorpholinyl)[6-[[3-(4-fluorophenyl)-5-methyl-4-isoxazolyl]methoxy]-3-pyridinyl]methanone

(1,1-Dioxido-4-thiomorpholinyl)[6-[[3-(4-fluorophenyl)-5-methyl-4-isoxazolyl]methoxy]-3-pyridinyl]methanone

CAS: 1159600-41-5

Formula: C₂₁H₂₀FN₃O₅S

Purity: %

Color and Shape: Solid

Molecular weight: 445.4640

Ref: IN-DA008YDC

Basmisanil

CAS: 1159600-41-5

Basmisanil

Purity: ≥98%

Molecular weight: 445.46g/mol

Ref: 54-BUP09649

Basmisanil

CAS: 1159600-41-5

Basmisanil

Purity: 98%

Molecular weight: 445.46g/mol

Ref: 54-PC108905

Basmisanil

CAS: 1159600-41-5

Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the

Formula: C₂₁H₂₀FN₃O₅S

Purity: 99.21% - 99.42%

Color and Shape: Solid

Molecular weight: 445.46

Ref: TM-T7165

BASMISANIL

CAS: 1159600-41-5

Purity: 98+%

Molecular weight: 445.4700012

Ref: 10-F819835

Basmisanil

Controlled Product

CAS: 1159600-41-5

Applications Basmisanil is a highly selective GABAAα5 negative allosteric modulator.
References Myers, J.F., et al.: J Cereb Blood Flow Metab., (2016); Liogier, d’A. X., et al.: Front Behav Neurosci., 9, 300 (2015);

Formula: C₂₁H₂₀FN₃O₅S

Color and Shape: Neat

Molecular weight: 445.46

Ref: TR-B118715