CAS 1159613-24-7

3’-Hydroxy Darunavir

CAS: 1159613-24-7

Formula: C₂₇H₃₇N₃O₈S

Color and Shape: White To Off-White Solid

Molecular weight: 563.67

Ref: 4Z-D-374

3?-Hydroxy Darunavir

Controlled Product

CAS: 1159613-24-7

Applications 3’-Hydroxy Darunavir is a metabolite of Darunavir (D193500), a novel inhibitor of human immunodeficiency virus protease and used in the treatment of HIV infection. It is a COVID19-related research product.
References Vermeir, M., et al.: Drug. Meta. Disp., 37, 809 (2009); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),

Formula: C₂₇H₃₇N₃O₈S

Color and Shape: Neat

Molecular weight: 563.66

Ref: TR-H931760

3-Hydroxy darunavir

CAS: 1159613-24-7

3-Hydroxy darunavir is a prodrug. It is hydrolyzed to its active form, darunavir, in the liver by esterases. 3-Hydroxy darunavir binds to the peptide receptor CXCR4 and inhibits HIV from entering the cell. 3-Hydroxy darunavir has also been shown to inhibit ion channels and Ligand-gated ion channels, which are important for neurotransmission. This drug is used as a research tool for Cell Biology and as an inhibitor of ion channels.

Formula: C₂₇H₃₇N₃O₈S

Purity: Min. 95%

Molecular weight: 563.7 g/mol

Ref: 3D-JWB61324

3'-Hydroxy Darunavir

CAS: 1159613-24-7

Formula: C₂₇H₃₇N₃O₈S

Molecular weight: 563.67

Ref: ST-EA-CP-D70013