CAS 1159683-24-5
:Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Description:
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a synthetic nucleoside derivative that serves as a phosphoramidite building block for oligonucleotide synthesis. This compound features a guanosine base, which is one of the four nucleobases in RNA, and is modified at the 5' and 3' positions to enhance its stability and reactivity during the synthesis of oligonucleotides. The presence of the bis(4-methoxyphenyl)phenylmethyl group at the 5' position contributes to the compound's hydrophobic characteristics, potentially influencing its solubility and interaction with other biomolecules. The 2'-O-methyl modification provides resistance to nuclease degradation, making it useful in therapeutic applications. The cyanoethyl phosphoramidite moiety at the 3' position is crucial for the coupling reactions in solid-phase oligonucleotide synthesis. Overall, this compound is significant in the field of molecular biology and genetic engineering, particularly in the development of RNA-based therapeutics and diagnostics.
Formula:C41H50N7O8P
Synonyms:- Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite
- Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
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