CAS 115976-93-7

PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE

Description:

Philanthotoxin 343 tris-trifluoroacetate, identified by its CAS number 115976-93-7, is a synthetic compound derived from the natural toxin found in the venom of certain wasps. This substance is characterized by its complex molecular structure, which includes multiple functional groups that contribute to its biological activity. Philanthotoxin 343 is known for its ability to inhibit specific ion channels, particularly in the nervous system, which can affect neurotransmission and signal propagation. Its trifluoroacetate form enhances its solubility and stability in various solvents, making it useful in biochemical research. The compound is primarily utilized in pharmacological studies to explore its effects on neuronal activity and potential therapeutic applications. However, due to its potent biological effects, it must be handled with caution in laboratory settings. As with many chemical substances, understanding its properties, including solubility, stability, and reactivity, is crucial for safe and effective use in research and potential applications.

Formula: C₂₃H₄₁N₅O₃

InChI: InChI=1S/C23H41N5O3/c1-2-7-22(30)28-21(18-19-8-10-20(29)11-9-19)23(31)27-17-6-16-26-14-4-3-13-25-15-5-12-24/h8-11,21,25-26,29H,2-7,12-18,24H2,1H3,(H,27,31)(H,28,30)/t21-/m0/s1

InChI key: InChIKey=DTWANULJDRVTFI-NRFANRHFSA-N

SMILES: [C@H](CC1=CC=C(O)C=C1)(C(NCCCNCCCCNCCCN)=O)NC(CCC)=O

Synonyms:

• (S)-PhTX 343
• (S)-Philanthotoxin 343
• (S)-Ptx 343
• (αS)-N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]benzenepropanamide
• Benzenepropanamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]-, (S)-
• Benzenepropanamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]-, (αS)-
• N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]-Nalpha-butanoyl-L-tyrosinamide
• PhTX-343, S-N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]-benzenepropanamide tris-trifluoroacetate
• Philanthotoxin 343
• Philanthotoxin 343 Tris(Trifluoroacetate) Salt
• Philanthotoxin 343 Tris-Trifluoroacetate Blocks Nmda-Gated Ion
• Phtx-343
• Ptx 343
• N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-Nα-butanoyl-L-tyrosinamide
• (S)-N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]benzenepropanamide
• N-[3-[4-(3-Aminopropylamino)butylamino]propyl]-Nα-butyryl-L-tyrosinamide
• S-N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]-benzenepropanamide tris-trifluoroacetate
• PhTX-343 TFA

PhTX-343 TFA

CAS: 115976-93-7

PhTX-343, a synthetic derivative of δ-philanthotoxin, inhibits NMDA ion channels.

Formula: C₂₃H₄₁N₅O₃

Color and Shape: Solid

Molecular weight: 435.60

Ref: TM-T34056