CAS 115992-91-1

(2S,3S)-5-(2-Aminoethyl)-3-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one

CAS: 115992-91-1

(2S,3S)-5-(2-Aminoethyl)-3-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one

Purity: 98%

Molecular weight: 330.41g/mol

Ref: 54-OR1063688

Diltiazem Impurity H (N,N,O-Tridesmethyl Desacetyl Diltiazem)

CAS: 115992-91-1

Formula: C₁₇H₁₈N₂O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 330.40

Ref: 4Z-D-0710

(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one

Controlled Product

CAS: 115992-91-1

Applications (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one is an impurity of diltiazem (D460620). Diltiazem Hydrochloride is a calcium channel blocker with vasodilating activity. Anti-anginal; anti-hypertensive; anti-arrhythmic (class IV).
References Sato, et al.: Arzneim.-Forsch., 21, 1338 (1971), Smirnov, S.R.: Eur. J. Pharmacol., 360, 81 (1998), Hansson, L., et al.: Lancet, 356, 359 (2000),

Formula: C₁₇H₁₈N₂O₃S

Color and Shape: White To Light Yellow

Molecular weight: 330.4

Ref: TR-A609220

(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one-d4

Controlled Product

CAS: 115992-91-1

Formula: C₁₇D₄H₁₄N₂O₃S

Color and Shape: Neat

Molecular weight: 334.426

Ref: TR-A609222

Diltiazem EP Impurity H

CAS: 115992-91-1

Diltiazem EP Impurity H is a metabolite of diltiazem that is used as an impurity standard for the drug product. Diltiazem EP Impurity H has a purity level of 99% and is soluble in water. It is synthesized by reacting diltiazem with nitric acid, then hydrolyzing the product to form the desired compound. Diltiazem EP Impurity H can be used as an analytical reference material or a pharmacopoeia for HPLC standards.
Diltiazem EP Impurity H is a metabolite of diltiazem that is used as an impurity standard for the drug product. Diltiazem EP Impurity H has a purity level of 99% and is soluble in water. It is synthesized by reacting diltiazem with nitric acid, then hydrolyzing the product to form the desired compound. Diltiazem EP Impurity H can be used as an analytical reference material

Formula: C₁₇H₁₈N₂O₃S

Purity: Min. 95%

Molecular weight: 330.4 g/mol

Ref: 3D-ID181761

N,N,O-Tridesmethyl Desacetyl Diltiazem

CAS: 115992-91-1

Formula: C₁₇H₁₈N₂O₃S

Molecular weight: 330.40

Ref: ST-EA-CP-D22033