CAS 1159977-10-2

[1,1'-Biphenyl]-2’-tetrazolo-4-carboxylic acid, [1,1'-biphenyl]-2’tetrazolo-4-ylmethyl ester (Losartan Impurity)

Description:

[1,1'-Biphenyl]-2’-tetrazolo-4-carboxylic acid, also known as Losartan Impurity, is a chemical compound characterized by its biphenyl structure, which consists of two phenyl rings connected by a single bond. The presence of a tetrazole ring, a five-membered heterocyclic compound containing four nitrogen atoms, contributes to its unique chemical properties, including potential biological activity. The carboxylic acid functional group (-COOH) indicates that the compound can participate in acid-base reactions and may exhibit polar characteristics, influencing its solubility in various solvents. Additionally, the ester derivative, [1,1'-biphenyl]-2’tetrazolo-4-ylmethyl ester, suggests that the compound can undergo esterification reactions, which may affect its reactivity and stability. This impurity is of interest in pharmaceutical chemistry, particularly in the context of drug development and quality control, as it may arise during the synthesis of Losartan, an antihypertensive medication. Understanding the characteristics of such impurities is crucial for ensuring the safety and efficacy of pharmaceutical products.

Formula: C₂₈H₂₀N₈O₂

Synonyms:

• "[1,1-Biphenyl]-2-tetrazolo-4-carboxylic acid, [1,1-biphenyl]-2-tetrazolo-4-ylmethyl ester"
• [1,1'-Biphenyl]-4-carboxylic acid, 2'-(2H-tetrazol-5-yl)-, [2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl ester
• [1,1'-Biphenyl]-2’-tetrazolo-4-carboxylic acid, [1,1'-biphenyl]-2’tetrazolo-4-ylmethyl ester (Losartan Impurity)

[1,1'-Biphenyl]-2’-tetrazolo-4-carboxylic acid, [1,1'-biphenyl]-2’-tetrazolo-4-ylmethyl ester (Losartan Impurity)

Controlled Product

CAS: 1159977-10-2

Applications Losartan impurity J.
References Duncia, J.V., et al.: J. Med. Chem., 33, 1312 (1990),

Formula: C₂₈H₂₀N₈O₂

Color and Shape: Neat

Molecular weight: 500.51

Ref: TR-B398000

[1,1'-Biphenyl]-2'-(2H-tetrazol-5-yl)-4-carboxylic acid, [1,1'-biphenyl]-(2'-(2H-tetrazol-5-yl)-4-yl)methyl ester

CAS: 1159977-10-2

Biphenyl-2'-(2H-tetrazol-5-yl)-4-carboxylic acid, [1,1'-biphenyl]-(2'-(2H-tetrazol-5-yl)-4-yl)methyl ester is a research and development impurity standard. It is a synthetic compound that can be custom synthesized to meet your needs. The product is available in high purity and pharmacopoeia grade. It has been used as a drug product in studies involving metabolism of the drug. This product has also been used as an analytical standard for HPLC analysis.

Formula: C₂₈H₂₀N₈O₂

Purity: Min. 95%

Molecular weight: 500.51 g/mol

Ref: 3D-IB18639