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CAS 1159977-13-5

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N-Boc-N-deshydroxyethyl Dasatinib

Description:
N-Boc-N-deshydroxyethyl Dasatinib is a chemical compound that serves as a derivative of Dasatinib, a potent tyrosine kinase inhibitor primarily used in the treatment of certain types of leukemia. The "N-Boc" designation indicates the presence of a tert-butoxycarbonyl (Boc) protecting group, which is commonly used in organic synthesis to protect amines during chemical reactions. The "N-deshydroxyethyl" portion suggests that this compound has been modified to remove a hydroxyethyl group, which can influence its pharmacological properties and solubility. This modification may enhance the compound's stability or alter its interaction with biological targets. The compound's molecular structure and functional groups contribute to its overall reactivity and potential applications in medicinal chemistry. As with many pharmaceutical compounds, understanding its characteristics, including solubility, stability, and biological activity, is crucial for its development and use in therapeutic contexts. Safety and handling precautions should be observed, as with all chemical substances, particularly those with biological activity.
Formula:C25H30ClN7O3S
Synonyms:
  • 1-Piperazinecarboxylic acid, 4-[6-[[5-[[(2-chloro-6-methylphenyl)amino]carbonyl]-2-thiazolyl]amino]-2-methyl-4-pyrimidinyl]-, 1,1-dimethylethyl ester
  • N-Boc-N-deshydroxyethyl Dasatinib
  • N-(2-Chloro-6-Methylphenyl)-2-[[2-Methyl-6-(1-(4-boc-piperazinyl))-4-pyriMidinyl]aMino]-5-thiazolecarboxaMide
  • 4-[6-[[5-[[(2-Chloro-6-Methylphenyl)aMino]carbonyl]-2-thiazolyl]aMino]-2-Methyl-4-pyriMidinyl]-1-piperazinecarboxylic Acid 1,1-DiMethylethyl Ester
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