CAS 1159977-56-6

5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1H-indole-2,3-dione

Description:

5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1H-indole-2,3-dione, with the CAS number 1159977-56-6, is a synthetic organic compound characterized by its complex molecular structure, which includes an indole core, a chloro substituent, and a benzisothiazole moiety. This compound features a piperazine ring, contributing to its potential biological activity, particularly in pharmacological applications. The presence of the indole and benzisothiazole groups suggests that it may exhibit interesting interactions with biological targets, possibly influencing neurotransmitter systems or other cellular pathways. Its chlorinated indole structure may enhance lipophilicity, affecting its solubility and permeability. The compound's unique arrangement of functional groups positions it as a candidate for further research in medicinal chemistry, particularly in the development of novel therapeutic agents. However, specific properties such as solubility, melting point, and biological activity would require empirical investigation to fully characterize its potential applications and safety profile.

Formula: C₂₁H₁₉ClN₄O₂S

InChI: InChI=1S/C21H19ClN4O2S/c22-16-12-17-15(19(27)21(28)23-17)11-13(16)5-6-25-7-9-26(10-8-25)20-14-3-1-2-4-18(14)29-24-20/h1-4,11-12H,5-10H2,(H,23,27,28)

InChI key: InChIKey=VWHQRPYTDLERQO-UHFFFAOYSA-N

SMILES: C(CC=1C=C2C(=CC1Cl)NC(=O)C2=O)N3CCN(C=4C=5C(SN4)=CC=CC5)CC3

Synonyms:

• 1H-Indole-2,3-dione, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-
• 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1H-indole-2,3-dione
• 5-[2-[4-(1,2-Benzisothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1H-indole-2,3-dione
• (Ziprasidone Impurity B)
• 3-Oxo Ziprasidone
• Ziprasidone IMpurity B
• Ziprasidone?EP Impurity B/ Ziprasidone?Related Compound B (3-Oxo Ziprasidone)
• Ziprasidone EP Impurity B
• 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1H-indole-2,3-dione
• Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
• Ziprasidone Impurity 2（Ziprasidone EP Impurity B）
• 5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindoline-2,3-dione

Ziprasidone Related Compound B (5-{2-[4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloroindoline-2,3-dione)

CAS: 1159977-56-6

Compounds containing a benzothiazole ring-system (whether or not hydrogenated), not further fused

Formula: C₂₁H₁₉ClN₄O₂S

Color and Shape: Dark Yellow Powder

Molecular weight: 426.09172

Ref: 45-1724420

5-(2-(4-(BENZO[D]ISOTHIAZOL-3-YL)PIPERAZIN-1-YL)ETHYL)-6-CHLOROINDOLINE-2,3-DIONE

CAS: 1159977-56-6

Formula: C₂₁H₁₉ClN₄O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 426.9192

Ref: IN-DA000HEL

Ziprasidone EP Impurity B (Ziprasidone USP Related Compound B)

CAS: 1159977-56-6

Formula: C₂₁H₁₉ClN₄O₂S

Color and Shape: Orange Red Solid

Molecular weight: 426.93

Ref: 4Z-Z-077

3-Oxo Ziprasidone

Controlled Product

CAS: 1159977-56-6

Applications (5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindoline-2,3-dione), is a compound related to Ziprasidone (Z485000), which is a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Used as an antipsychotic.
References Bench, C.J., et al.: Psychopharmacology, 112, 308 (1993), Goldstein, J.M.: Exp. Opin. Invest. Drugs, 4, 291 (1995)

Formula: C₂₁H₁₉ClN₄O₂S

Color and Shape: Neat

Molecular weight: 426.92

Ref: TR-B203575

Ziprasidone EP Impurity B

CAS: 1159977-56-6

Formula: C₂₁H₁₉ClN₄O₂S

Molecular weight: 426.92

Ref: ST-EA-CP-Z3002