CAS 116-42-7

Sulfaproxyline

Description:

Sulfaproxyline, with the CAS number 116-42-7, is a sulfonamide antibiotic that belongs to the class of compounds known as sulfa drugs. It is characterized by its ability to inhibit bacterial growth by interfering with the synthesis of folic acid, which is essential for bacterial metabolism. This compound typically appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Sulfaproxyline is primarily used in veterinary medicine for the treatment of bacterial infections in animals. Its mechanism of action involves competitive inhibition of the enzyme dihydropteroate synthase, which is crucial in the folate synthesis pathway. While effective against a range of gram-positive and some gram-negative bacteria, the use of sulfaproxyline and other sulfonamides has declined due to the emergence of antibiotic resistance and the availability of more effective alternatives. Safety and efficacy profiles are important considerations in its application, and it is essential to adhere to regulatory guidelines when using this compound in any context.

Formula: C₁₆H₁₈N₂O₄S

InChI: InChI=1S/C16H18N2O4S/c1-11(2)22-14-7-3-12(4-8-14)16(19)18-23(20,21)15-9-5-13(17)6-10-15/h3-11H,17H2,1-2H3,(H,18,19)

InChI key: InChIKey=FBFBRAFXKGRRHI-UHFFFAOYSA-N

SMILES: S(NC(=O)C1=CC=C(OC(C)C)C=C1)(=O)(=O)C2=CC=C(N)C=C2

Synonyms:

• Benzamide, N-((4-aminophenyl)sulfonyl)-4-(1-methylethoxy)- (9CI)
• Benzamide, N-[(4-aminophenyl)sulfonyl]-4-(1-methylethoxy)-
• Benzamide, p-isopropoxy-N-sulfanilyl-
• Benzamide, p-isopropoxy-N-sulfanilyl- (8CI)
• G 13289
• G 14289
• N(sup 1)-(4-Isopropoxybenzoyl)sulfanilamide
• N(sup1)-(4-Isopropoxybenzoyl)-p-aminobenzenesulfonamide
• N(sup1)-(4-Isopropoxybenzoyl)sulfanilamide
• N(sup1)-(p-Isopropoxybenzoyl)sulfanilamide
• N-[(4-Aminophenyl)sulfonyl]-4-(1-methylethoxy)benzamide
• N-[(4-aminophenyl)sulfonyl]-4-(propan-2-yloxy)benzamide
• N1-(4-Isopropoxybenzoyl)sulfanilamide
• N¹-(4-Isopropoxybenzoyl)-p-aminobenzenesulfonamide
• N¹-(4-Isopropoxybenzoyl)sulfanilamide
• N¹-(p-Isopropoxybenzoyl)sulfanilamide
• Nsc 120646
• Sulfaproxilina
• Sulfaproxilina [INN-Spanish]
• Sulfaproxiline
• Sulfaproxylin
• Sulfaproxyline [INN]
• Sulfaproxylinum
• Sulfaproxylinum [INN-Latin]
• Sulphaproxyline
• Unii-Yr841R53Vw
• p-((4-Isopropoxybenzoyl)amino)benzenesulfonamide
• p-Isopropoxy-N-sulfanilylbenzamide

Sulfaproxiline

CAS: 116-42-7

Sulfaproxiline (Sulfaproxylin) is a synthetic antibacterial drug of sulfonamide.

Formula: C₁₆H₁₈N₂O₄S

Purity: 99.52%

Color and Shape: Solid

Molecular weight: 334.39

Ref: TM-T13033

Benzamide, N-[(4-aminophenyl)sulfonyl]-4-(1-methylethoxy)-

CAS: 116-42-7

Formula: C₁₆H₁₈N₂O₄S

Purity: 95%

Color and Shape: Solid

Molecular weight: 334.3901

Ref: IN-DA000BCR

Sulfaproxiline

CAS: 116-42-7

Sulfaproxiline

Purity: ≥98%

Molecular weight: 334.39g/mol

Ref: 54-BUP08897

Sulfaproxiline

CAS: 116-42-7

Sulfaproxiline is a drug used to treat microbial infection. It has been shown to have beneficial effects on symptoms associated with microbial infections, such as lowering blood pressure and reducing the risk of choroidal neovascularization. Sulfaproxiline is an analog of the anti-hypertensive drug clonidine that is used to lower blood pressure by acting on alpha-2 adrenergic receptors in the kidney. It has been shown to inhibit malonic acid production from glucose in rats, which may be due to its ability to inhibit mitochondrial succinic semialdehyde dehydrogenase. Sulfaproxiline also inhibits a monoclonal antibody that targets CD4+ T cells, which may contribute to its immunosuppressive properties.
Sulfaproxiline is currently being studied for potential use in treating cancerous tumors. It has been shown that sulfaproxiline can cause cell cycle arrest and apoptosis in tumor cells, which

Formula: C₁₆H₁₈N₂O₄S

Purity: Min. 95%

Molecular weight: 334.4 g/mol

Ref: 3D-AAA11642