CAS 1160170-00-2

Rivaroxaban Diol (Mixture of Diastereomers)

Description:

Rivaroxaban Diol, identified by the CAS number 1160170-00-2, is a chemical compound that serves as a metabolite of the anticoagulant drug rivaroxaban. This substance is characterized by its diol functional groups, which contribute to its solubility and reactivity. As a mixture of diastereomers, it exhibits different spatial arrangements of atoms, leading to variations in its physical and chemical properties, such as melting point and boiling point. Rivaroxaban itself is a selective inhibitor of Factor Xa, playing a crucial role in the coagulation cascade, and its diol form may retain some pharmacological activity or serve as an intermediate in metabolic pathways. The compound is typically analyzed using techniques such as chromatography and mass spectrometry to determine its purity and concentration. Safety data sheets indicate that, like many pharmaceuticals, it should be handled with care, considering potential toxicity and environmental impact. Overall, rivaroxaban diol represents an important aspect of the pharmacokinetics and metabolism of anticoagulant therapies.

Formula: C₁₉H₂₀ClN₃O₆S

Synonyms:

• 2-Thiophenecarboxamide, 5-chloro-N-[[(5S)-3-[4-[(2-hydroxyacetyl)(2-hydroxyethyl)amino]phenyl]-2-oxo-5-oxazolidinyl]methyl]-
• Rivaroxaban Diol Q: What are the applications of
• Rivaroxaban DiolQ: What is
• Rivaroxaban Diol Q: What is the CAS Number of
• Rivaroxaban Diol
• Rivaroxaban Diol Q: What is the storage condition of
• 5-Chloro-N-[[(5S)-3-[4-[(2-hydroxyacetyl)(2-hydroxyethyl)aMino]phenyl]-2-oxo-5-oxazolidinyl]Methyl]-
• Rivaroxaban Impurity 85（Rivaroxaban Diol）
• Rivaroxaban diol metabolite
• (Mixture of Diastereomers)
• Rivaroxaban Impurity 85

Rivaroxaban Open Oxomorpholine Ring ((S)-5-chloro-N-((3-(4-(2-hydroxy-N-(2-hydroxyethyl)acetamido) phenyl)-2-oxooxazolidin-5-yl)methyl)thiophene-2-carboxamide)

CAS: 1160170-00-2

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₉H₂₀ClN₃O₆S

Color and Shape: White Off-White Solid

Molecular weight: 453.07613

Ref: 45-1A02240

Rivaroxaban Metabolite 5

CAS: 1160170-00-2

Formula: C₁₉H₂₀ClN₃O₆S

Color and Shape: White To Off-White Solid

Molecular weight: 453.89

Ref: 4Z-R-293

Rivaroxaban Impurity 16

CAS: 1160170-00-2

Formula: C₁₉H₁₈ClN₃O₆S

Color and Shape: White To Off-White Solid

Molecular weight: 451.89

Ref: 4Z-R-2930

Rivaroxaban Diol

Controlled Product

CAS: 1160170-00-2

Applications A metabolite of Rivaroxaban (R538000).
References Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005), Roehrig, S., et al.: J. Med. Chem., 48, 5900 (2005), Biemond, B., et al.: Thromb. Haemost., 97, 471 (2007), Lang, D., et al.: Drug Metab. Dispos., 37, 1046 (2009),

Formula: C₁₉H₂₀ClN₃O₆S

Color and Shape: White To Off-White

Molecular weight: 453.9

Ref: TR-R538010

Rivaroxaban Diol

CAS: 1160170-00-2

Formula: C₁₉H₂₀ClN₃O₆S

Molecular weight: 453.9

Ref: ST-EA-CP-R17074

Rivaroxaban diol

CAS: 1160170-00-2

Rivaroxabandiol is a metabolite of Rivaroxaban, which is a potent and selective direct inhibitor of coagulation factor Xa (FXa) with an IC50 of 0.7 nM and a Ki of 0.4 nM.

Formula: C₁₉H₂₀ClN₃O₆S

Color and Shape: Solid

Molecular weight: 453.897

Ref: TM-TYD-02008