CAS 1160247-92-6

1-[(4-Methoxyphenyl)methyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione

Description:

1-[(4-Methoxyphenyl)methyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione is a synthetic organic compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This compound features a methoxy group and a trifluoromethoxy group, which contribute to its unique chemical properties and potential biological activity. The presence of the methoxyphenylmethyl substituent enhances its lipophilicity, potentially influencing its interaction with biological membranes. The trifluoromethoxy group is notable for its electron-withdrawing properties, which can affect the compound's reactivity and stability. This compound may exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry. Its molecular structure suggests potential applications in drug development, particularly in targeting specific biological pathways. However, detailed studies on its biological activity, toxicity, and pharmacokinetics would be necessary to fully understand its potential uses and safety profile.

Formula: C₁₇H₁₂F₃NO₄

InChI: InChI=1S/C17H12F3NO4/c1-24-11-4-2-10(3-5-11)9-21-14-7-6-12(25-17(18,19)20)8-13(14)15(22)16(21)23/h2-8H,9H2,1H3

InChI key: InChIKey=CKLGZXFOLMHCMC-UHFFFAOYSA-N

SMILES: C(N1C=2C(C(=O)C1=O)=CC(OC(F)(F)F)=CC2)C3=CC=C(OC)C=C3

Synonyms:

• 1H-Indole-2,3-dione, 1-[(4-methoxyphenyl)methyl]-5-(trifluoromethoxy)-
• 1-(4-Methoxy-benzyl)-5-trifluoromethoxy-1H-indole-2,3-dione
• VU 0238429
• 1-[(4-Methoxyphenyl)methyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione
• ML 129
• 1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin

1H-Indole-2,3-dione, 1-[(4-methoxyphenyl)methyl]-5-(trifluoromethoxy)-

CAS: 1160247-92-6

Formula: C₁₇H₁₂F₃NO₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 351.2767

Ref: IN-DA000BF3

VU 0238429

CAS: 1160247-92-6

VU 0238429

Purity: ≥95%

Molecular weight: 351.28g/mol

Ref: 54-BUP09888

VU0238429

CAS: 1160247-92-6

Formula: C₁₇H₁₂F₃NO₄

Molecular weight: 351.28

Ref: 7W-GK2147

VU 0238429

CAS: 1160247-92-6

VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).

Formula: C₁₇H₁₂F₃NO₄

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 351.28

Ref: TM-T8007

VU 0238429

CAS: 1160247-92-6

VU 0238429 is a nicotinic acetylcholine inhibitor that is used to study the effects of cholinergic drugs on biological systems. It binds to nicotinic acetylcholine receptors and blocks the binding of acetylcholine, preventing the activation of muscle tissue. VU 0238429 has been shown to have a significant effect on dopamine levels in rats, which may be due to its inhibition of dopamine uptake by neurons. VU 0238429 has also been shown to improve performance in animals on a rotarod test. The drug was administered at different concentrations, and it was found that an increase in concentration leads to an increase in duration before the rat falls off the rod.

Formula: C₁₇H₁₂F₃NO₄

Purity: Min. 95%

Molecular weight: 351.28 g/mol

Ref: 3D-KWB24792