CAS 1160556-64-8

2′-(Dicyclohexylphosphino)-N2,N2,N6,N6-tetramethyl[1,1′-biphenyl]-2,6-diamine

Description:

2′-(Dicyclohexylphosphino)-N2,N2,N6,N6-tetramethyl[1,1′-biphenyl]-2,6-diamine, identified by its CAS number 1160556-64-8, is a specialized organophosphorus compound that features a biphenyl backbone substituted with a tetramethylated diamine and a dicyclohexylphosphino group. This compound is characterized by its unique structural arrangement, which imparts significant steric hindrance and electronic properties, making it useful in various catalytic applications, particularly in transition metal catalysis. The presence of the dicyclohexylphosphino moiety enhances its ability to stabilize metal complexes, thereby facilitating reactions such as cross-coupling and other transformations in organic synthesis. Additionally, the compound's solubility and reactivity can be influenced by the bulky cyclohexyl groups, which may also affect its interaction with substrates and catalysts. Overall, this compound is of interest in the field of organometallic chemistry and catalysis due to its distinctive properties and potential applications in synthetic methodologies.

Formula: C₂₈H₄₁N₂P

InChI: InChI=1S/C28H41N2P/c1-29(2)25-19-13-20-26(30(3)4)28(25)24-18-11-12-21-27(24)31(22-14-7-5-8-15-22)23-16-9-6-10-17-23/h11-13,18-23H,5-10,14-17H2,1-4H3

InChI key: InChIKey=DRNAQRXLOSUHBQ-UHFFFAOYSA-N

SMILES: P(C1=C(C=CC=C1)C2=C(N(C)C)C=CC=C2N(C)C)(C3CCCCC3)C4CCCCC4

Synonyms:

• (2-Indanylidene)malononitrile
• 2-(2-Dicyclohexylphosphanylphenyl)-1-N,1-N,3-N,3-N-tetramethylbenzene-1,3-diamine
• 2-(Dicyanomethylen)indan
• 2′-(Dicyclohexylphosphino)-N2,N2,N6,N6-tetramethyl-[1,1′-biphenyl]-2,6-diamine
• 2′-(Dicyclohexylphosphino)-N²,N²,N⁶,N⁶-tetramethyl[1,1′-biphenyl]-2,6-diamine
• CPhos
• Malononitrile,(2-Indanylidene)
• [1,1′-Biphenyl]-2,6-diamine, 2′-(dicyclohexylphosphino)-N²,N²,N⁶,N⁶-tetramethyl-
• [1,1′-Biphenyl]-2,6-diamine, 2′-(dicyclohexylphosphino)-N2,N2,N6,N6-tetramethyl-
• 2-Dicyclohexylphosphino-2',6'-bis(diMethylaMino)-1,1'-biphenyl

2-Dicyclohexylphosphino-2',6'-bis(dimethylamino)-1,1'-biphenyl, min. 98% CPhos

CAS: 1160556-64-8

2-Dicyclohexylphosphino-2',6'-bis(dimethylamino)-1,1'-biphenyl, min. 98% CPhos

Formula: C₂₈H₄₁N₂P

Purity: min. 98%

Color and Shape: off-white to orange xtl.

Molecular weight: 436.61

Ref: 08-15-1147

[1,1'-Biphenyl]-2,6-diamine, 2'-(dicyclohexylphosphino)-N2,N2,N6,N6-tetramethyl-

CAS: 1160556-64-8

Formula: C₂₈H₄₁N₂P

Purity: 95%

Color and Shape: Solid

Molecular weight: 436.6123

Ref: IN-DA000BI1

CPhos

CAS: 1160556-64-8

CPhos

Purity: 97%

Molecular weight: 436.62g/mol

Ref: 54-OR73258

CPhos

CAS: 1160556-64-8

Purity: 95%

Molecular weight: 436.6239929

Ref: 10-F601410

2-Dicyclohexylphosphino-2',6'-bis(N,N-dimethylamino)biphenyl

CAS: 1160556-64-8

2-Dicyclohexylphosphino-2',6'-bis(N,N-dimethylamino)biphenyl (PCP-DMAP) is a phosphorus compound that is used for the synthesis of aryl chlorides. It has been validated as an effective reagent for the conversion of aryl chlorides to aryl halides. PCP-DMAP can be used in peptidomimetic synthesis and profiling. It is also useful in the synthesis of natural products where activation with N,N-dimethylchloramine (DMC) is required. PCP-DMAP can be used as an efficient alternative to other methods for activation with DMC, using less time and producing less waste. This compound has been shown to be stable against hydrolysis and oxidation in both acidic and basic media, making it a good reagent for use under these conditions. PCP-DMAP can also be used in the synthesis

Formula: C₂₈H₄₁N₂P

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 436.61 g/mol

Ref: 3D-FD46061

CPhos

Controlled Product

CAS: 1160556-64-8

Applications CPhos, is used as a catalyst in the synthetic preparation of palladium-catalyzed Negishi coupling of secondary alkylzinc halides with aryl bromides and chlorides.
References Han, C., et al.: J. Am. Chem. Soc., 131, 7532 (2009)

Formula: C₂₈H₄₁N₂P

Color and Shape: Neat

Molecular weight: 436.61

Ref: TR-C781430