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CAS 116094-23-6

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Insulin (human),28B-L-aspartic acid-

Description:
Insulin (human), specifically the variant known as 28B-L-aspartic acid, is a peptide hormone crucial for glucose metabolism and regulation in the human body. It is composed of 51 amino acids and has a molecular weight that reflects its peptide structure. This particular variant features an aspartic acid substitution at the 28th position of the B-chain, which can influence its biological activity and pharmacokinetics. Insulin functions primarily by facilitating the uptake of glucose into cells, thereby lowering blood sugar levels. It also plays a role in lipid and protein metabolism. The CAS number 116094-23-6 identifies this specific insulin variant, which is used in therapeutic applications, particularly for managing diabetes. Insulin is typically administered via injection due to its protein nature, which prevents it from being effective when taken orally. The stability, solubility, and bioavailability of this insulin variant are critical for its efficacy in clinical settings, making it an important subject of study in biochemistry and pharmacology.
Formula:C256H381N65O79S6
Synonyms:
  • Insulin(ox), 8A-L-threonine-10A-L-isoleucine-28B-L-aspartic acid-30B-L-threonine-
  • AspB28-insulin (human)
  • B28-Asp-insulin
  • Ina-X 14
  • Insulin X 14
  • Insulin aspart
  • NovoLog
  • NovoLog Mix 70/30
  • NovoMix 30
  • NovoRapid30 Mix
  • See more synonyms
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