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CAS 1161925-41-2

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  • NVP-BQS481
    Targetmol
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    NVP-BQS481

    CAS:
    NVP-BQS481 (Compound 1) is a selective inhibitor of spindle motor protein 5 (Eg5), with an IC50 of less than 0.5 nM. It demonstrates significant anti-mitotic and anti-tumor activities, exhibiting an IC50 of 0.09 nM against SK-OV-3ip cells. NVP-BQS481 is suitable for use as a cytotoxic payload in the synthesis of antibody-drug conjugates (ADCs).
    Formula:C27H33F3N4O2
    Color and Shape:Solid
    Molecular weight:502.57

    Ref: TM-T212559