CAS 1163-36-6: Clemizole hydrochloride

Description: Clemizole hydrochloride is a synthetic compound primarily recognized for its antihistaminic properties. It belongs to the class of diphenylmethylpiperazines and is often utilized in the treatment of allergic conditions. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Its mechanism of action involves antagonism of histamine H1 receptors, which helps alleviate symptoms associated with allergic reactions. Additionally, Clemizole has been studied for its potential neuroprotective effects and its ability to modulate certain neurotransmitter systems. However, it is essential to note that while it has therapeutic applications, the use of Clemizole hydrochloride may be accompanied by side effects, including sedation and anticholinergic effects. As with any medication, proper dosage and monitoring are crucial to minimize adverse reactions. Overall, Clemizole hydrochloride is a noteworthy compound in the realm of antihistamines, with a unique profile that warrants further investigation in clinical settings.

Formula: C₁₉H₂₀ClN₃·ClH

InChI: InChI=1S/C19H20ClN3.ClH/c20-16-9-7-15(8-10-16)13-23-18-6-2-1-5-17(18)21-19(23)14-22-11-3-4-12-22;/h1-2,5-10H,3-4,11-14H2;1H

InChI key: InChIKey=DNFMJYXRIMLMBZ-UHFFFAOYSA-N

SMILES: Cl.ClC1=CC=C(C=C1)CN2C=3C=CC=CC3N=C2CN4CCCC4

Synonyms:

• 1-(4-Chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzo[d]imidazole hydrochloride
• 1-(4-Chlorobenzyl)-2-(pyrrolidinylmethyl)-1,3-benzimidazole hydrochloride
• 1-[4-Chlorophenyl)methyl]-2-(1-pyrrolidinylmethyl)-1H-benzimidazole, Monohydrochloride
• 1-p-Chlorobenzyl-2-(1-pyrrolidinylmethyl)benzimidazole hydrochloride
• 1-p-Chlorobenzyl-2-pyrrolidylmethyl benzimidazole hydrochloride
• 1-{[1-(4-chlorobenzyl)-1H-benzimidazol-2-yl]methyl}pyrrolidinium chloride
• 1H-Benzimidazole, 1-[(4-chlorophenyl)methyl]-2-(1-pyrrolidinylmethyl)-, hydrochloride (1:1)
• 1H-Benzimidazole, 1-[(4-chlorophenyl)methyl]-2-(1-pyrrolidinylmethyl)-, monohydrochloride
• Al 20
• Allercur
• Benzimidazole, 1-(p-chlorobenzyl)-2-(1-pyrrolidinylmethyl)-, monohydrochloride
• Histacuran
• Klemidox
• Reactrol

Clemizole Hydrochloride

CAS: 1163-36-6442-52-4

• Formula: C₁₉H₂₀ClN₃·HCl
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 362.30

1H-Benzimidazole, 1-[(4-chlorophenyl)methyl]-2-(1-pyrrolidinylmethyl)-, hydrochloride (1:1)

CAS: 1163-36-6

• Formula: C₁₉H₂₁Cl₂N₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 362.2961

Clemizole hydrochloride

CAS: 1163-36-6

• Formula: C₁₉H₂₀ClN₃
• Purity: ≥ 98.0%
• Color and Shape: White to off-white solid
• Molecular weight: 325.84

Clemizole hydrochloride

CAS: 1163-36-6

Clemizole hydrochloride blocks H1 histamine receptors and inhibits HCV replication and NS4B RNA binding.

• Formula: C₁₉H₂₁Cl₂N₃
• Purity: 99.91%
• Color and Shape: Solid
• Molecular weight: 362.3

Clemizole HCl

CAS: 1163-36-6

• Formula: C₁₉H₂₀ClN₃·HCl
• Molecular weight: 325.84 36.46

Clemizole hydrochloride

CAS: 1163-36-6

Inhibits TRPC5 channel blocker; histamine (H1) receptor antagonist

• Formula: C₁₉H₂₀ClN₃·HCl
• Purity: Min. 95%
• Color and Shape: White Off-White Powder
• Molecular weight: 362.3

Clemizole Hydrochloride

CAS: 1163-36-6

Applications Clemizole Hydrochloride inhibits Hepatitis C RNA replication in cell culture through the suppression of …

• Formula: C₁₉H₂₀ClN₃·ClH
• Color and Shape: Neat
• Molecular weight: 362.30