CAS 442-52-4

Clemizole

Description:

Clemizole is a chemical compound that belongs to the class of antihistamines, primarily known for its use in the treatment of allergic conditions. It is characterized by its ability to antagonize histamine H1 receptors, thereby alleviating symptoms associated with allergies such as itching, sneezing, and runny nose. The molecular structure of clemizole includes a diphenylmethyl group, which contributes to its pharmacological activity. It is typically administered in oral form and has been studied for its potential effects beyond antihistaminic activity, including possible neuroprotective properties. Clemizole is also noted for its relatively low sedative effects compared to other antihistamines, making it a preferred choice in certain clinical scenarios. However, like many medications, it may have side effects, including drowsiness or gastrointestinal disturbances. Its safety profile and efficacy have been evaluated in various studies, although it is less commonly used in contemporary practice compared to newer antihistamines. As with any medication, it is essential to use clemizole under the guidance of a healthcare professional.

Formula: C₁₉H₂₀ClN₃

InChI: InChI=1S/C19H20ClN3/c20-16-9-7-15(8-10-16)13-23-18-6-2-1-5-17(18)21-19(23)14-22-11-3-4-12-22/h1-2,5-10H,3-4,11-14H2

InChI key: InChIKey=CJXAEXPPLWQRFR-UHFFFAOYSA-N

SMILES: C(N1C=2C(N=C1CN3CCCC3)=CC=CC2)C4=CC=C(Cl)C=C4

Synonyms:

• 1-(4-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole
• 1-(p-Chlorobenzyl)-2-pyrrolidylmethylenebenzimidazole
• 1-[(4-Chlorophenyl)methyl]-2-(1-pyrrolidinylmethyl)-1H-benzimidazole
• 1-p-Chlorobenzyl-2-(1-pyrrolidinylmethyl)benzimidazole
• 1-p-Chlorobenzyl-2-pyrrolidino-methylbenzimidazole
• 1H-Benzimidazole, 1-((4-chlorophenyl)methyl)-2-(1-pyrrolidinylmethyl)-
• Benzimidazole, 1-(p-chlorobenzyl)-2-(1-pyrrolidinylmethyl)-
• Benzimidazole, 1-(p-chlorobenzyl)-2-(1-pyrrolidinylmethyl)- (8CI)
• Clemizol
• Clemizol [INN-Spanish]
• Clemizole [INN:BAN]
• Clemizolo
• Clemizolo [DCIT]
• Clemizolum
• Clemizolum [INN-Latin]
• Depocural
• Histacur
• Histakool
• Lergopenin
• Nsc 46261
• Pyrrolidine, 1-[(1-p-chlorobenzyl-2-benzimidazolyl)methyl]-

Clemizole

CAS: 442-52-4

Formula: C₁₉H₂₀ClN₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 325.8352

Ref: IN-DA00DB5I

Clemizole

CAS: 442-52-4

Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.

Formula: C₁₉H₂₀ClN₃

Purity: 98% - 99.65%

Color and Shape: Solid

Molecular weight: 325.84

Ref: TM-T1822

1-(4-Chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzo[d]imidazole

CAS: 442-52-4

Formula: C₁₉H₂₀ClN₃

Purity: 99%

Molecular weight: 325.84

Ref: IN-DG121872

Clemizole

CAS: 442-52-4

Formula: C₁₉H₂₀ClN₃

Molecular weight: 325.8

Ref: BE-BePure-24394

Clemizole

Controlled Product

CAS: 442-52-4

Clemizole is a biocompatible polymer that has been shown to be effective against resistant mutants in vitro. It also has the ability to inhibit locomotor activity in mice and prevent the development of hepatitis. Clemizole is an inhibitor that binds to benzalkonium chloride, which is an antiseptic agent used in many household products. Clemizole may also be useful for treating skin cancer.

Formula: C₁₉H₂₀ClN₃

Purity: Min. 95%

Molecular weight: 325.84 g/mol

Ref: 3D-AAA44252