CAS 116308-96-4

Ludipress

Description:

Ludipress is a pharmaceutical excipient primarily used as a binder and filler in tablet formulations. It is a co-processed excipient composed of a combination of polyvinylpyrrolidone (PVP) and mannitol, which enhances its functional properties. This substance is characterized by its excellent flowability, compressibility, and ability to form cohesive granules, making it ideal for direct compression processes. Ludipress exhibits good moisture absorption properties, which can help maintain the stability of moisture-sensitive active pharmaceutical ingredients. Additionally, it is known for its low hygroscopicity, ensuring that tablets maintain their integrity in various environmental conditions. The substance is generally recognized as safe for use in pharmaceuticals and is compatible with a wide range of active ingredients, making it a versatile choice in the formulation of solid dosage forms. Its unique characteristics contribute to improved tablet hardness, disintegration, and dissolution profiles, ultimately enhancing the bioavailability of the active compounds in the final product.

Formula: C₁₂H₂₂O₁₁·(C₆H₉NO)x·H₂O

InChI: InChI=1S/C12H22O11.C6H9NO.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;1-2-7-5-3-4-6(7)8;/h3-20H,1-2H2;2H,1,3-5H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;;/m1../s1

InChI key: InChIKey=YLOBNWMOSAEBBD-FEFFVFSNSA-N

SMILES: O([C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O)[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O.O.C(=C)N1C(=O)CCC1

Synonyms:

• 2-Pyrrolidinone, 1-ethenyl-, homopolymer, mixt. contg.
• Ludipress
• Ludipress LCE
• α-D-Glucopyranose, 4-O-β-D-galactopyranosyl-, monohydrate, mixt. with 1-ethenyl-2-pyrrolidinone homopolymer

α-D-Glucopyranose, 4-O-β-D-galactopyranosyl-, monohydrate, mixt. with 1-ethenyl-2-pyrrolidinone homopolymer

CAS: 116308-96-4

Formula: C₁₈H₃₁NO₁₂

Molecular weight: 453.4382

Ref: IN-DA000C6D