CAS 116314-52-4

Entacapone Impurity 2（Entacapone EP Impurity B）

Description:

Entacapone Impurity 2, also known as Entacapone EP Impurity B, is a chemical compound associated with the pharmaceutical agent entacapone, which is used primarily in the treatment of Parkinson's disease. This impurity is characterized by its specific molecular structure, which is a derivative of the entacapone molecule, and it may exhibit distinct physical and chemical properties compared to the parent compound. Typically, impurities like this can affect the efficacy and safety of pharmaceutical formulations, making their characterization crucial in drug development and quality control. The compound is likely to have a defined melting point, solubility profile, and spectral characteristics (such as NMR and mass spectrometry data) that can be used for identification and quantification. Regulatory guidelines often require the assessment of such impurities to ensure that they remain within acceptable limits in pharmaceutical products. Understanding the behavior and characteristics of Entacapone Impurity 2 is essential for ensuring the quality and safety of medications containing entacapone.

Formula: C₁₂H₁₀N₂O₆

Synonyms:

• 2-Propenoic acid, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-, ethyl ester
• Entacapone Impurity 2（Entacapone EP Impurity B）

OR 545

Controlled Product

CAS: 116314-52-4

Applications OR 545 acts as a methyltransferase inhibitor used as an anticancer agent.
References Lotta, T. et al.: J. Comp-Aid. Mol. Des., 6, 253 (1992); Backstrom, R. et al.: J. Med. Chem., 32, 841 (1989);

Formula: C₁₂H₁₀N₂O₆

Color and Shape: Neat

Molecular weight: 278.22

Ref: TR-O671000

2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-2-propenoic acid ethyl ester

CAS: 116314-52-4

2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-2-propenoic acid ethyl ester is a potential drug that has been shown to inhibit the activation of LPA1 receptor. It is also known to inhibit the activity of ion channels such as TRPV1 and TRPA1. This compound has been shown to be effective in inhibiting the activity of peptides and antibodies, which are important in cell biology and research tools for biology laboratory.

Formula: C₁₂H₁₀N₂O₆

Purity: Min. 95%

Molecular weight: 278.22 g/mol

Ref: 3D-REA31452