CAS 116339-68-5

Imidazo[2,1-b]thiazole,6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)-, hydrochloride (1:2)

Description:

Imidazo[2,1-b]thiazole, 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)-, hydrochloride (1:2) is a synthetic compound characterized by its unique bicyclic structure, which incorporates both imidazole and thiazole rings. This compound typically exhibits a range of biological activities, making it of interest in medicinal chemistry, particularly for its potential as an antimicrobial or anticancer agent. The presence of the 4-fluorophenyl and 4-pyridinyl substituents enhances its pharmacological properties, potentially influencing its interaction with biological targets. As a hydrochloride salt, it is likely to be more soluble in water compared to its free base form, which can facilitate its use in various formulations. The compound's molecular weight, solubility, and stability can vary based on environmental conditions and the presence of other substances. Safety and handling precautions should be observed, as with any chemical, due to potential toxicity or reactivity. Further studies are often required to fully elucidate its mechanism of action and therapeutic potential.

Formula: C₁₆H₁₂FN₃SClH

Synonyms:

• Imidazo[2,1-b]thiazole,6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)-, dihydrochloride (9CI)
• Skf86002A2

SKF 86002 dihydrochloride

CAS: 116339-68-5

SKF 86002 is a tyrosine kinase inhibitor that has been shown to inhibit cancer cells from proliferating by modulating the expression of albumin. SKF 86002 has also been shown to be effective against acute lymphoblastic leukemia and cancer metastasis. SKF 86002 binds to the cell surface receptor, leading to inhibition of the phosphorylation of tyrosine residues on proteins in the cell membrane, which prevents the activation of cellular signal transduction pathways. SKF 86002 also inhibits chemoresistance mediated by serum albumin by binding to it and preventing its function as an enzyme.

Formula: C₁₆H₁₂FN₃S·2HCl

Purity: Min. 95%

Molecular weight: 370.27 g/mol

Ref: 3D-REA33968

SKF-86002 dihydrochloride

CAS: 116339-68-5

p38 MAP kinase inhibitor

Formula: C₁₆H₁₄Cl₂FN₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 370.27

Ref: TM-T23365