CAS 116371-66-5

Cytidine 5'-(trihydrogen diphosphate), 2'-deoxy-2',2'-difluoro-

Description:

Cytidine 5'-(trihydrogen diphosphate), 2'-deoxy-2',2'-difluoro- is a modified nucleoside analog that plays a role in biochemical research and potential therapeutic applications. This compound features a cytidine base, which is a pyrimidine nucleoside, linked to a diphosphate group. The presence of difluorination at the 2' position of the sugar moiety enhances its stability and alters its interaction with nucleic acid synthesis enzymes. The trihydrogen diphosphate group indicates that it has three protons associated with the phosphate moieties, which can influence its reactivity and binding properties. Such modifications can affect the compound's ability to participate in metabolic pathways, potentially inhibiting or mimicking natural nucleotides. This substance is of interest in the study of nucleic acid metabolism, antiviral drug development, and cancer research, as it may interfere with the replication of nucleic acids in pathogenic organisms or cancer cells. Its unique structural characteristics make it a valuable tool in molecular biology and medicinal chemistry.

Formula: C₉H₁₃F₂N₃O₁₀P₂

Gemcitabine Diphosphate Ditetrabutylammonium Salt

CAS: 116371-66-5

Formula: C₉H₁₁F₂N₃O₁₀P₂·2C₁₆H₃₆N

Molecular weight: 421.14 2*242.47

Ref: 4Z-G-2623

Gemcitabine Diphosphate Triethylamine Salt (>90%)

Controlled Product

CAS: 116371-66-5

Applications Gemcitabine Diphosphate is a phosphorylated metabolite of Gemcitabine (G305000), an antineoplastic agent.
References Baker, C., et al.: J. Med. Chem., 34, 1879 (1991), Huang, P., et al.: Cancer Res., 51, 6110 (1991), Plunkett, W., et al.: Nucleosides Nucleotides, 16, 1261 (1997),

Formula: C₂₇H₅₈F₂N₆O₁₀P₂

Purity: >90%

Color and Shape: White To Off-White

Molecular weight: 726.73

Ref: TR-G305025

Gemcitabine diphosphate triethylamine salt

CAS: 116371-66-5

Gemcitabine diphosphate triethylamine salt is an inhibitor that has been shown to be effective in the treatment of various forms of cancer. It works by inhibiting the activity of kinases, which are enzymes involved in the regulation of cell growth and division. Gemcitabine diphosphate triethylamine salt is a prodrug that is converted to its active form, gemcitabine, in vivo. This drug has been shown to inhibit the uptake of xylose by cancer cells, leading to decreased protein synthesis and induction of apoptosis. In addition, it has been found to be effective against human and Chinese medicinal tumor cells. Gemcitabine diphosphate triethylamine salt is a promising treatment option for patients with cancer who have not responded well to traditional chemotherapy or radiation therapy.

Formula: C₉H₁₃F₂N₃O₁₀P₂

Purity: Min. 95%

Molecular weight: 423.16 g/mol

Ref: 3D-REA37166

Gemcitabine 5-Diphosphate

CAS: 116371-66-5

Formula: C₉H₁₃F₂N₃O₁₀P₂

Molecular weight: 423.16

Ref: ST-EA-CP-G7026