CAS 116371-67-6: 2'-Deoxy-2',2'-difluoro-5'-cytidylic Acid
Description:2'-Deoxy-2',2'-difluoro-5'-cytidylic acid, commonly referred to as a modified nucleoside, is a synthetic derivative of cytidine. This compound features two fluorine atoms substituted at the 2' position of the ribose sugar, which enhances its stability and alters its interaction with nucleic acids. The presence of fluorine can influence the compound's biological activity, potentially affecting its role in nucleic acid synthesis and function. As a nucleotide analog, it may be utilized in research related to antiviral therapies or as a tool in molecular biology to study nucleic acid processes. The modification can also impact its solubility, binding affinity, and overall pharmacokinetics. The CAS number 116371-67-6 uniquely identifies this compound in chemical databases, facilitating its study and application in various scientific fields. Overall, 2'-Deoxy-2',2'-difluoro-5'-cytidylic acid exemplifies how structural modifications can lead to significant changes in the properties and functionalities of nucleoside derivatives.
Formula:C9H12F2N3O7P
InChI:InChI=1/C9H12F2N3O7P/c10-9(11)6(15)4(3-20-22(17,18)19)21-7(9)14-2-1-5(12)13-8(14)16/h1-2,4,6-7,15H,3H2,(H2,12,13,16)(H2,17,18,19)/t4-,6+,7-/m1/s1
- Synonyms:
- Gemcitabine Monophosphate