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CAS 116430-58-1

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olsalazine-O-sulfate

Description:
Olsalazine-O-sulfate is a chemical compound primarily recognized for its role in the treatment of inflammatory bowel diseases, particularly ulcerative colitis. It is a derivative of olsalazine, which is a prodrug that gets converted into its active form in the colon. The compound features a sulfonate group, which contributes to its solubility and bioactivity. Olsalazine-O-sulfate exhibits anti-inflammatory properties, primarily through the inhibition of leukotriene synthesis and modulation of immune responses in the gastrointestinal tract. Its mechanism of action involves the release of 5-aminosalicylic acid (5-ASA) upon cleavage in the colon, which exerts a local anti-inflammatory effect. The compound is typically administered orally and is characterized by its stability in acidic environments, ensuring that it reaches the colon intact. As with many pharmaceuticals, potential side effects may include gastrointestinal disturbances, and its use should be monitored by healthcare professionals. Overall, olsalazine-O-sulfate represents a targeted therapeutic approach in managing chronic inflammatory conditions of the intestines.
Formula:C14H10N2O9S
InChI:InChI=1/C14H10N2O9S/c17-11-3-1-7(5-9(11)13(18)19)15-16-8-2-4-12(25-26(22,23)24)10(6-8)14(20)21/h1-6,16H,(H,18,19)(H,20,21)(H,22,23,24)/b15-7+
Synonyms:
  • Olsalazine-O-sulphate
  • 5-[(2E)-2-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)hydrazinyl]-2-(sulfooxy)benzoic acid
  • Olsalazine-O-sulfate
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Found 3 products.
  • Olsalazine-O-Sulfate
    TLC
    + Info

    Olsalazine-O-Sulfate

    CAS:
    Formula:C14H7N2O9S·3Na
    Molecular weight:379.28 3 22.99

    Ref: 4Z-O-2211

    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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  • Olsalazine O-Sulfate Sodium Salt
    TRC
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    Olsalazine O-Sulfate Sodium Salt

    Controlled Product
    CAS:
    Formula:C14H7N2Na3O9S
    Color and Shape:Neat
    Molecular weight:448.248

    Ref: TR-O586005

    250mg
    12,795.00€
  • Olsalazine o-sulfate sodium salt
    Biosynth
    + Info

    Olsalazine o-sulfate sodium salt

    CAS:
    <p>Olsalazine o-sulfate sodium salt is a medicinal compound that has been shown to have potential as an apoptosis-inducing agent for cancer cells. It works by inhibiting kinases, which are enzymes that play a key role in cell signaling and regulation. Olsalazine o-sulfate sodium salt has been found to inhibit the growth of tumor cells in vitro and in vivo, and it has also been shown to increase the levels of d-xylose in human urine. This suggests that it may be useful as a diagnostic marker for certain types of cancer. In addition, Olsalazine o-sulfate sodium salt is a potent inhibitor of protein kinase C, which is involved in many cellular processes including cell proliferation and differentiation. Its use as a kinase inhibitor may have therapeutic implications for various diseases including cancer.</p>
    Formula:C14H10N2O9S
    Purity:Min. 95%
    Molecular weight:382.3 g/mol

    Ref: 3D-REA43058

    25mg
    1,095.00€
    50mg
    1,523.00€