CAS 1165-40-8: Andrographin

Description: Andrographin, with the CAS number 1165-40-8, is a bioactive compound primarily derived from the plant Andrographis paniculata, commonly known as the "king of bitters." This compound is a diterpenoid lactone and is known for its various pharmacological properties, including anti-inflammatory, antioxidant, and antimicrobial activities. Andrographin is often studied for its potential therapeutic effects in treating conditions such as respiratory infections, liver disorders, and certain types of cancer. The substance exhibits a bitter taste, which is characteristic of many compounds derived from medicinal plants. Its mechanism of action is believed to involve modulation of immune responses and inhibition of pro-inflammatory cytokines. Additionally, andrographin has been explored for its role in enhancing the bioavailability of other therapeutic agents. Due to its diverse biological activities, it has garnered interest in both traditional medicine and modern pharmacology, although further research is necessary to fully elucidate its mechanisms and potential clinical applications.

Formula: C₁₈H₁₆O₆

InChI: InChI=1S/C18H16O6/c1-21-13-7-5-4-6-10(13)14-8-11(19)16-12(20)9-15(22-2)17(23-3)18(16)24-14/h4-9,20H,1-3H3

InChI key: InChIKey=AJMNTEFGXPRZHG-UHFFFAOYSA-N

SMILES: O=C1C=C(OC2=C(OC)C(OC)=CC(O)=C12)C=3C=CC=CC3OC

Synonyms:

• 2'-O-Methylskullcapflavone I
• 5-Hydroxy-2',7,8-trimethoxyflavone
• 5-Hydroxy-2′,7,8-trimethoxyflavone
• 5-Hydroxy-7,8-dimethoxy-2-(2-methoxyphenyl)-4H-1-benzopyran-4-one
• Andrographin
• Flavone, 5-hydroxy-2′,7,8-trimethoxy-
• Flavone,5-hydroxy-2',7,8-trimethoxy- (7CI,8CI)
• Skullcapflavone I 2'-methylether
• Skullcapflavone I 2′-methyl ether
• 4H-1-Benzopyran-4-one, 5-hydroxy-7,8-dimethoxy-2-(2-methoxyphenyl)-

5-Hydroxy-7,8,2'-trimethoxyflavone

CAS: 1165-40-8

5-Hydroxy-7,8,2'-trimethoxyflavone is a flavonoid that has been shown to have antimicrobial properties. It is an …

• Formula: C₁₈H₁₆O₆
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 328.32 g/mol