CAS 1165740-62-4
:Immunoglobulin G1, anti-(CD antigen CD70) (human-mouse monoclonal h1F6 heavy chain), disulfide with human-mouse monoclonal h1F6 light chain, dimer
Description:
Immunoglobulin G1 (IgG1) is a type of antibody that plays a crucial role in the immune response by recognizing and binding to specific antigens. The specific variant mentioned, anti-(CD antigen CD70), is a human-mouse chimeric monoclonal antibody designed to target the CD70 antigen, which is involved in T-cell activation and proliferation. This antibody is composed of heavy and light chains linked by disulfide bonds, forming a dimeric structure that enhances its stability and functionality. The heavy chain is derived from a human source, while the light chain is from a mouse source, allowing for improved specificity and reduced immunogenicity in therapeutic applications. IgG1 antibodies are characterized by their ability to activate complement and mediate antibody-dependent cellular cytotoxicity (ADCC). The presence of the CD70 target makes this antibody particularly relevant in cancer immunotherapy, as CD70 is often overexpressed in various malignancies. Overall, this monoclonal antibody represents a significant tool in targeted therapies and research involving immune modulation.
Formula:Unspecified
Synonyms:- SGN 70
- Vorsetuzumab
- Immunoglobulin G1, anti-(CD antigen CD70) (human-mouse monoclonal h1F6 heavy chain), disulfide with human-mouse monoclonal h1F6 light chain, dimer
- h 1F6
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Found 3 products.
Vorsetuzumab
CAS:<p>Vorsetuzumab (Anti-Human CD70 Recombinant Antibody) is a monoclonal antibody targeting the CD70 antibody.</p>Purity:SDS-PAGE:95% SEC-HPLC:99.29%Color and Shape:LiquidMolecular weight:146.1 kDa
