CAS 116649-85-5
:Ramatroban
Description:
Ramatroban is a chemical compound classified as a selective thromboxane A2 receptor antagonist. It is primarily known for its potential therapeutic applications, particularly in the treatment of conditions such as asthma and allergic rhinitis. The molecular structure of Ramatroban features a complex arrangement that includes a carboxylic acid group, contributing to its biological activity. It exhibits anti-inflammatory properties by inhibiting the action of thromboxane A2, a potent vasoconstrictor and platelet aggregator. Ramatroban is typically administered in oral form and has been studied for its effects on bronchial hyperreactivity and other allergic responses. Its pharmacokinetics indicate a moderate absorption profile, with metabolism occurring primarily in the liver. The compound is generally well-tolerated, with a safety profile that has been evaluated in clinical studies. Overall, Ramatroban represents a significant interest in pharmacology due to its targeted action on specific receptors involved in inflammatory processes.
Formula:C21H21FN2O4S
InChI:InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1
InChI key:InChIKey=LDXDSHIEDAPSSA-OAHLLOKOSA-N
SMILES:C(CC(O)=O)N1C2=C(C=3C1=CC=CC3)C[C@H](NS(=O)(=O)C4=CC=C(F)C=C4)CC2
Synonyms:- (3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid
- 3-[(3R)-3-[(4-Fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid
- 3-[(3R)-3-{[(4-fluorophenyl)sulfonyl]amino}-1,2,3,4-tetrahydro-9H-carbazol-9-yl]propanoic acid
- 3R-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid
- 9H-Carbazole-9-propanoic acid, 3-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-, (3R)-
- 9H-Carbazole-9-propanoic acid, 3-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-, (R)-
- BAY-u 3405
- Baynas
- Ramatroban
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Found 10 products.
9H-CARBAZOLE-9-PROPANOIC ACID, 3-[[(4-FLUOROPHENYL)SULFONYL]AMINO]-1,2,3,4-TETRAHYDRO-, (3R)-
CAS:Formula:C21H21FN2O4SPurity:98%Color and Shape:SolidMolecular weight:416.4658Ramatroban
CAS:<p>Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis.</p>Formula:C21H21FN2O4SPurity:98.75% - >99.99%Color and Shape:Crystalline SolidMolecular weight:416.47Ramatroban-d4
CAS:Formula:C21H17D4FN2O4SColor and Shape:White To Off-White SolidMolecular weight:420.49(R)-3-(3-(4-Fluorophenylsulfonamido)-3,4-Dihydro-1H-Carbazol-9(2H)-Yl)Propanoic Acid
CAS:(R)-3-(3-(4-Fluorophenylsulfonamido)-3,4-Dihydro-1H-Carbazol-9(2H)-Yl)Propanoic AcidPurity:98%Molecular weight:416.47g/molRamatroban
CAS:Formula:C21H21FN2O4SPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:416.47Ramatroban
CAS:<p>Dual inhibitor of thromboxane receptor and DP2 postanoid receptor</p>Formula:C21H21FN2O4SPurity:Min. 95%Color and Shape:PowderMolecular weight:416.47 g/molRamatroban
CAS:Controlled Product<p>Applications A thromboxane receptor antagonist for use in the treatment of coronary artery disease.<br>References Rahman, M., et al.: Int. Immunopharmacol., 6, 1736 (2006), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Sandham, D., et al.: Bioorg. Med. Chem. Lett., 19, 4794 (2009),<br></p>Formula:C21H21FN2O4SColor and Shape:NeatMolecular weight:416.47
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