CAS: 116666-63-8 - MIBEFRADIL

Formula: C₂₉H₄₀Cl₂FN₃O₃

InChI: InChI=1S/C29H38FN3O3.2ClH/c1-20(2)28-23-12-11-22(30)18-21(23)13-14-29(28,36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26;;/h5-6,8-9,11-12,18,20,28H,7,10,13-17,19H2,1-4H3,(H,31,32);2*1H/t28-,29-;;/m0../s1

InChI key: InChIKey=MTJLQTFHJIHXIX-GDUXWEAWSA-N

SMILES: Cl.O=C(OC1(CCC2=CC(F)=CC=C2C1C(C)C)CCN(C)CCCC3=NC=4C=CC=CC4N3)COC

Synonyms:

• (1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl methoxyacetate dihydrochloride
• (1S-Cis)-Orid
• 2-(2-((3-(1H-Benzimidazol-2-Yl)Propyl)Methylamino)Ethyl)-Aceticaci
• 6-Fluoro-1,2,3,4-Tetrahydro-1-(1-Methylethyl)-2-Naphthalenylester,Dihydrochl
• Acetic acid, 2-methoxy-, (1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, hydrochloride (1:2)
• Acetic acid, methoxy-, (1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, dihydrochloride
• Acetic acid, methoxy-, 2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, dihydrochloride, (1S-cis)-
• Mibefradil diHCl
• Mibefradil dihydrochloride
• Mibefradil hydrate dihydrochloride
• Posicor
• Ro 40-5967
• Ro 40-5967 hydrate, (1S,2S)-2-[2[[3-(2-Benzimidazolylpropyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate hydrate dihydrochloride
• Ro 40-5967/001
• Ro40-5967/001

Acetic acid, 2-methoxy-, (1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, hydrochloride (1:2)

CAS: 116666-63-8

• Formula: C₂₉H₄₀Cl₂FN₃O₃
• Purity: ≥98%
• Color and Shape: Solid
• Molecular weight: 568.5506

Mibefradil dihydrochloride

CAS: 116666-63-8

• Formula: C₂₉H₃₈FN₃O₃· 2HCl·xH₂O
• Molecular weight: 568.55 (anhydrous)

Mibefradil dihydrochloride

CAS: 116666-63-8

Mibefradil dihydrochloride (Ro 40-5967 (dihydrochloride)) is an blocker of calcium channel with moderate selectivity for …

• Formula: C₂₉H₄₀Cl₂FN₃O₃
• Purity: 99.72%
• Color and Shape: Solid
• Molecular weight: 568.55

Mibefradil hydrochloride

CAS: 116666-63-8

Mibefradil is a calcium channel antagonist with the highest selectivity for T- and L-type channels, …

• Formula: C₂₉H₃₈FN₃O₃·2HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 568.55 g/mol

Mibefradil Dihydrochloride (>90%)

CAS: 116666-63-8

Applications Mibefradil dihydrochloride is selectively blocks Ca2+ entry into cells by inhibiting T-type Ca2+ channels.

• Formula: C₂₉H₃₈FN₃O₃• 2HCl
• Purity: >90%
• Color and Shape: Neat
• Molecular weight: 568.55

Mibefradil Dihydrochloride Hydrate

CAS: 116666-63-81391053-69-2

Applications Mibefradil Dihydrochloride is a nondihydropyridine calcium channel blocker with potent vasodilator but weak inotropic …

• Formula: C₂₉H₃₈FN₃O₃•xHO•HCl
• Color and Shape: White to Off-White Solid
• Molecular weight: 495.64 + x(18.02) + (36.46)