CAS 1168152-06-4

Nintedanib Impurity 14

CAS: 1168152-06-4

Formula: C₂₁H₁₉NO₅

Molecular weight: 365.13

Ref: 4Z-N-066028

(3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester

Controlled Product

CAS: 1168152-06-4

Applications (3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester is an impurity of Intedanib (I666650), an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases.
References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)

Formula: C₂₁H₁₉NO₅

Color and Shape: Neat

Molecular weight: 365.379

Ref: TR-A173865

Nintedanib Impurity 14

CAS: 1168152-06-4

Formula: C₂₁H₁₉NO₅

Molecular weight: 365.13

Ref: ST-EA-CP-N24082