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CAS 116817-11-9

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(RS)-Duloxetine hydrochloride

Description:
(RS)-Duloxetine hydrochloride is a pharmaceutical compound primarily used as an antidepressant and anxiolytic agent. It belongs to the class of serotonin-norepinephrine reuptake inhibitors (SNRIs), which function by increasing the levels of serotonin and norepinephrine in the brain, thereby improving mood and alleviating anxiety. The compound is a white to off-white crystalline powder, soluble in water and methanol, and has a molecular formula that reflects its complex structure. Its stereochemistry is significant, as it exists as a racemic mixture, meaning it contains equal parts of both enantiomers, which can influence its pharmacological effects. Duloxetine is commonly prescribed for major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain. The hydrochloride salt form enhances its stability and solubility, making it suitable for oral administration. As with any medication, it is essential to consider potential side effects and contraindications, and it should be used under medical supervision.
Formula:C18H20ClNOS
InChI:InChI=1/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/m1./s1
Synonyms:
  • N-Methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine hydrochloride
  • Duloxetime
  • (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride (1:1)
  • (RS)-N-Methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine hydrochloride
  • Duloxetine hydrochloride
  • N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aminium chloride
  • (3R)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aminium chloride
  • Duloxetine HCl
  • N-Methyl-gama-(1-naphthalenyloxy)-2-thiophenepropana
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