CAS 116817-86-8

2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γS)-, (2Z)-2-butenedioate (1:1)

Description:

2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γS)-, (2Z)-2-butenedioate (1:1), with CAS number 116817-86-8, is a chemical compound characterized by its complex structure that includes a thiophene ring, a naphthalene moiety, and an amine functional group. This compound features a stereocenter, indicated by the (γS) designation, which suggests specific spatial arrangements of its atoms that can influence its biological activity and reactivity. The presence of the butenedioate moiety indicates potential for reactivity typical of unsaturated carboxylic acids, which may participate in various chemical reactions such as esterification or conjugation. The compound's unique combination of aromatic and heterocyclic components may contribute to its solubility properties and interactions with biological systems. Overall, this substance may be of interest in medicinal chemistry and materials science, particularly in the development of pharmaceuticals or as a building block for more complex organic synthesis. However, specific applications and biological activities would require further investigation and characterization.

Formula: C₁₈H₁₉NOS·C₄H₄O₄

SMILES: O([C@@H](CCNC)C1=CC=CS1)C=2C3=C(C=CC2)C=CC=C3.C(=C\C(O)=O)\C(O)=O

Synonyms:

• 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (S)-, (Z)-2-butenedioate (1:1)
• 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γS)-, (2Z)-2-butenedioate (1:1)

Duloxetine-d7 Maleate

Controlled Product

CAS: 116817-86-8

Applications Labelled Duloxetine, which is used as an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI).
References Wong, D.T., et al.: Neuropsychopharmacology, 8, 23 (1993), Fuller, R.W., et al.: J. Pharmacol. Exp. Ther., 269, 132 (1994), Sharma, A., et al.: J. Clin. Pharmacol., 40, 161 (2000)

Formula: C₂₂H₁₆D₇NO₅S

Color and Shape: Neat

Molecular weight: 420.53

Ref: TR-D721003

Duloxetine-d3 Maleate

Controlled Product

CAS: 116817-86-8

Applications Duloxetine-d3 Maleate, is the labeled analogue of Duloxetine (D721000), which is used as an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI).
References Wong, D.T., et al.: Neuropsychopharmacology, 8, 23 (1993), Fuller, R.W., et al.: J. Pharmacol. Exp. Ther., 269, 132 (1994), Sharma, A., et al.: J. Clin. Pharmacol., 40, 161 (2000)

Formula: C₁₈D₃H₁₆NOS·C₄H₄O₄

Color and Shape: White Solid

Molecular weight: 416.50

Ref: TR-D721004

Duloxetine maleate

Controlled Product

CAS: 116817-86-8

Duloxetine maleate is an apoptosis-inducing drug that belongs to the class of anticancer inhibitors. It has been shown to be effective against a variety of tumor types, including thyroid and cancer cells. Duloxetine maleate is an analog inhibitor of kinases, which are enzymes involved in cell signaling pathways that regulate cell growth and division. This drug has been studied extensively in Chinese hamster ovary (CHO) and human urine protein models, where it has demonstrated potent anticancer activity by inducing apoptosis in cancer cells. Additionally, studies have shown that duloxetine maleate can inhibit the growth of tumors by blocking the activity of specific kinases involved in cancer cell proliferation. Overall, duloxetine maleate is a promising drug for the treatment of various types of cancer.

Formula: C₂₂H₂₃NO₅S

Purity: Min. 95%

Molecular weight: 413.5 g/mol

Ref: 3D-REA81786