CAS 116840-18-7

Uridine 5'-(tetrahydrogen triphosphate),5-[(1E)-3-amino-1-propenyl]-2'-deoxy-

Description:

Uridine 5'-(tetrahydrogen triphosphate), 5-[(1E)-3-amino-1-propenyl]-2'-deoxy- is a nucleotide derivative characterized by its unique structure, which includes a uridine base linked to a triphosphate group and an amino propenyl substituent. This compound is notable for its role in biochemical processes, particularly in nucleotide metabolism and as a potential signaling molecule. The presence of the triphosphate moiety suggests that it may participate in energy transfer or serve as a substrate for various enzymatic reactions. The amino propenyl group can influence the compound's reactivity and interactions with biological macromolecules, potentially affecting its biological activity. Additionally, the 2'-deoxy modification indicates that it lacks a hydroxyl group at the 2' position of the ribose sugar, which can impact its stability and function in nucleic acid synthesis. Overall, this compound's structural features contribute to its significance in biochemical research and potential therapeutic applications.

Formula: C₁₂H₂₀N₃O₁₄P₃

5-Aminoallyl 2'-deoxyuridine 5'-triphosphate lithium salt - 100mM aqueous solution

CAS: 116840-18-7

5-Aminoallyl 2'-deoxyuridine 5'-triphosphate lithium salt - 100mM aqueous solution is a novel nucleoside analog with antiviral and anticancer activity. It has been shown to inhibit the replication of HIV-1 in human peripheral blood mononuclear cells and to inhibit tumor growth in mice. This drug also inhibits DNA synthesis, which may be due to its ability to inhibit ribonucleotide reductase and deoxynucleotide reductase, enzymes that are necessary for DNA synthesis.

Formula: C₁₂H₂₀N₃O₁₄P₃·xLi

Purity: Min. 95%

Color and Shape: Colorless Powder

Molecular weight: 523.22 g/mol

Ref: 3D-NA32074

5-Aminoallyl 2'-deoxyuridine 5'-triphosphate sodium salt - 100mM aqueous solution

Controlled Product

CAS: 116840-18-7

5-Aminoallyl 2'-deoxyuridine 5'-triphosphate sodium salt is a nucleoside with antiviral and anticancer activities. It is a modified nucleoside that has been used as an antiviral agent against herpes simplex virus and Epstein-Barr virus. 5-Aminoallyl 2'-deoxyuridine 5'-triphosphate sodium salt can be used to inhibit the growth of tumor cells by inhibiting the production of DNA, RNA, and protein.

Formula: C₁₂H₂₀N₃O₁₄P₃·xNa

Purity: Min. 95%

Molecular weight: 523.22 g/mol

Ref: 3D-NA46883

5-Aminoallyl 2'-deoxyuridine 5'-triphosphate sodium salt

Controlled Product

CAS: 116840-18-7

5-Aminoallyl 2'-deoxyuridine 5'-triphosphate sodium salt is a novel anticancer nucleoside that is modified with an amino group at the 2' position. This modification increases the stability of 5-Aminoallyl 2'-deoxyuridine 5'-triphosphate sodium salt and enhances its ability to inhibit DNA synthesis. In addition, this nucleoside has been shown to be a potent antiviral agent against herpes simplex virus type 1 and HIV-1 by inhibiting viral DNA polymerase.
5-Aminoallyl 2'-deoxyuridine 5'-triphosphate sodium salt can be used in the preparation of antigens for immunotherapy and vaccine development, as well as in diagnostic applications such as in the diagnosis of cancer by detecting tumor cells.

Formula: C₁₂H₂₀N₃O₁₄P₃·xNa

Purity: Min. 95%

Ref: 3D-NA166366