CAS 116919-18-7

BIOTIN-MALEIMIDE

CAS: 116919-18-7

Formula: C₂₀H₂₉N₅O₅S

Purity: 95%

Color and Shape: Solid

Molecular weight: 451.5398

Ref: IN-DA008Y5V

Biotin-maleimide

CAS: 116919-18-7

Biotin-maleimide is a biotin conjugate that has been shown to bind to the amino acid residues in the active site of DNA polymerase. It inhibits the synthesis of DNA by competitively inhibiting the binding of tetracycline to the bacterial ribosome. This antibiotic is used in model systems and has been shown to be active against Proteus vulgaris, Escherichia coli K-12, and Klebsiella pneumoniae. Biotin-maleimide also inhibits prostaglandin production by binding to cyclooxygenase, which prevents activation of prostaglandin synthase. Biotin-maleimide has been shown to inhibit inflammation in animal models as well as reduce acid formation in human cells. The drug is used for treatment of autoimmune diseases such as rheumatoid arthritis or Crohn's disease.

Formula: C₂₀H₂₉N₅O₅S

Purity: Min. 95%

Molecular weight: 451.5 g/mol

Ref: 3D-REA91918